Results 41 to 50 of about 1,313,066 (193)
Diagnostics, 2023 Parkinson’s disease is the second most common neurodegenerative disorder, affecting 2–3% of the population of patients >65 years. Although the standard diagnosis of PD is clinical, neuroimaging plays a key role in the evaluation of patients who present ...
Ferdinando Corica +8 more
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TSPO imaging in parkinsonian disorders [PDF]
, 2016 Microglial activation is a key aspect of the neuroinflammatory process in neurodegenerative disorders including idiopathic and atypical parkinsonian disorders.
Alexander Gerhard, Gerhard, Alexander
core +1 more source
Advanced Science, EarlyView.Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters +12 more
wiley +1 more source
Nocturnal Manifestations of Atypical Parkinsonian Disorders
Journal of Parkinson’s Disease, 2014 Although nocturnal disturbances are increasingly recognized as an integral part of the continuum of daytime manifestations of Parkinson's disease (PD), there is still little evidence in the medical literature to support the occurrence of these complex ...
Roongroj Bhidayasiri +2 more
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Advanced Science, EarlyView.This study proposes a patch‐type tremor monitoring system based on high‐repeatable fibrous crack‐based strain sensor, capable of simultaneously measuring tremor in multiple locations such as thumb, index, and wrist. Through clinical trials involving Parkinson's disease and essential tremor patients, the proposed system demonstrates its potential as a ...
Chiwon Song +12 more
wiley +1 more source
Atypical parkinsonian disorders
Chinese Journal of Contemporary Neurology and Neurosurgery, 2011 DOI：10.3969/j.issn.1672-6731.2011.01 ...
Yue HUANG +3 more
doaj
Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation
Advanced Science, EarlyView.Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang +7 more
wiley +1 more source
Spinocerebellar ataxia 2 presenting as Parkinsonism: two families report and literatures review
Chinese Journal of Contemporary Neurology and Neurosurgery, 2022 Objective To summarize the clinical, imaging and genetic characteristics of spinocerebellar ataxia 2 (SCA2) families presenting as Parkinsonism. Methods and Results Two families with autosomal dominant SCA2 with Parkinson's syndrome diagnosed by genetic ...
WAN Ya⁃lan +8 more
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Genetic Variants of Na+,K+‐ATPase Associated With Neurological Disorders: A Systematic Review
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Neurological disorders encompass a wide range of severe symptoms and manifestations, many of which are associated with genetic variants that affect ionic homeostasis. Na+,K+‐ATPase, a transmembrane enzyme responsible for maintaining electrochemical gradients in cells, plays a crucial role in neuronal excitability and brain function.
Giovana Kummer da Rosa +3 more
wiley +1 more source
Affective symptoms in progressive supranuclear palsy
Journal of Geriatric Mental Health, 2014 Progressive supranuclear palsy is an unusual neurodegenerative disorder, which superficially resembles Parkinson′s disease, and the initial manifestations are characterized by depression, akinesia and mild cognitive impairment.
K S Shaji, K S Jyothi
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