Results 21 to 30 of about 65,290 (261)

Basal ganglia role in learning rewarded actions and executing previously learned choices: Healthy and diseased states [PDF]

open access: yes, 2020
The basal ganglia (BG) is a collection of nuclei located deep beneath the cerebral cortex that is involved in learning and selection of rewarded actions. Here, we analyzed BG mechanisms that enable these functions.
Atwood, Brady   +2 more
core   +1 more source

Organothiophosphate Induced Acute and Reversible Parkinsonism: Case Report and Literature Review [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2021
Introduction: Organophosphate compound poisoning is one of the most common causes for admission to the Medical Intensive Care Unit. Parkinsonism is a primary neurotoxic manifestation of organophosphate intoxication.
PRASHANT THAKUR, C SELVAKUMAR, V Kumar
doaj   +1 more source

Neuronal entropy depends on the level of alertness in the parkinsonian globus pallidus in vivo [PDF]

open access: yes, 2014
A new working hypothesis of Parkinson's disease (PD) proposes to focus on the central role of entropy increase in the basal ganglia (BG) in movement disorders. The conditions necessary for entropy increase in vivo are, however, still not fully described.
Andres, Daniela Sabrina   +3 more
core   +3 more sources

Priming mesenchymal stem cells with uric acid enhances neuroprotective properties in parkinsonian models

open access: yesJournal of Tissue Engineering, 2021
Mesenchymal stem cells (MSCs) are a potential source of cell-based disease-modifying therapy in Parkinsonian disorders. A promising approach to develop in vitro culture methods that mimic natural MSC niche is cell priming.
Ha Na Kim   +4 more
doaj   +1 more source

Focused ultrasound and deep brain stimulation for Parkinsonism – Review of literature to investigate tradeoff between safety and efficacy

open access: yesSaudi Journal for Health Sciences, 2022
Parkinsonism is a movement disorder, mostly caused by the neurodegenerative Parkinson's disease (PD), the second most common movement disorder. Its symptoms include rigidity, slow movement, tremor, and disruption of balance.
Uthman Alshenqiti   +4 more
doaj   +1 more source

Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid. [PDF]

open access: yes, 2016
BackgroundClinical diagnosis of parkinsonian syndromes like Parkinson's disease (PD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) is hampered by overlapping symptomatology and lack of diagnostic biomarkers, and definitive ...
Boman, Andrea   +8 more
core   +1 more source

Atypical parkinsonism: An Update. [PDF]

open access: yes, 2013
Purpose of review: This update discusses novel aspects on genetics, diagnosis, and treatments of atypical parkinsonism published over the past 2 years. Recent findings: A genome-wide association study identified new genetic risk factors for progressive ...
Hoeglinger, GU, Stamelou, M
core   +1 more source

Diagnostic Evaluation of 99mTc-TRODAT-1 SPECT in Parkinsonism [PDF]

open access: yesJournal of Research in Clinical Medicine, 2021
Background Parkinsonism as a group of movement disorders, exhibit similar clinical presentation. Therefore, clinically differentiating these diseases is difficult. We investigated the diagnostic value of 99m Tc-TRODAT-1 SPECT in this setting.
Zahra Babaei Aghdam   +5 more
doaj   +1 more source

Impaired perception of biological motion in Parkinson’s disease [PDF]

open access: yes, 2016
OBJECTIVE: We examined biological motion perception in Parkinson’s disease (PD). Biological motion perception is related to one’s own motor function and depends on the integrity of brain areas affected in PD, including posterior superior temporal sulcus.
Cronin-Golomb, Alice   +3 more
core   +1 more source

Comparison of 6-[18F]FDOPA PET with Nigrosome 1 detection in patients with parkinsonism

open access: yesEJNMMI Research, 2021
Background The functional 6-[18F]FDOPA positron emission tomography (PET) can be a helpful tool in differentiating parkinsonism with dopaminergic deficiency from clinically similar differential diagnoses.
Enrico Michler   +5 more
doaj   +1 more source

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