Results 21 to 30 of about 1,313,066 (193)
Journal of Tissue Engineering, 2021 Mesenchymal stem cells (MSCs) are a potential source of cell-based disease-modifying therapy in Parkinsonian disorders. A promising approach to develop in vitro culture methods that mimic natural MSC niche is cell priming.
Ha Na Kim +4 more
doaj +1 more source
Flt3 ligand does not differentiate between Parkinsonian disorders
, 2014 Differential diagnosis of parkinsonian disorders is challenging because of overlapping symptoms, especially during early stages of disease. No validated biomarkers are available for early and accurate diagnosis of multiple system atrophy and other ...
Holmberg, Björn +5 more
core +2 more sources
Novel biomarkers for parkinsonian disorders [PDF]
, 2023 Parkinsonian disorders (PS) are a heterogeneous group of neurodegenerative diseases characterised by the presence of parkinsonism. Parkinson’s disease (PD) is the most common PS, characterised by the accumulation of alpha-synuclein (αSyn) in Lewy ...
Fernandes Gomes, Bárbara
core +2 more sources
Comparison of 6-[18F]FDOPA PET with Nigrosome 1 detection in patients with parkinsonism
EJNMMI Research, 2021 Background The functional 6-[18F]FDOPA positron emission tomography (PET) can be a helpful tool in differentiating parkinsonism with dopaminergic deficiency from clinically similar differential diagnoses.
Enrico Michler +5 more
doaj +1 more source
Differential patterns of internally generated responses in parkinsonian disorders
, 2020 Internally generated responses are centrally affected in parkinsonian disorders. This study investigated the cognitive components crucial for response generation as reflected in performance on verbal and non-verbal fluency tasks, which require voluntary ...
Silburn, Peter +8 more
core +1 more source
Relationship Between Swallowing Function and Maximum Phonation Time in Patients With Parkinsonism [PDF]
Annals of Rehabilitation Medicine, 2018 Objective To identify the relationship between maximum phonation time (MPT) and swallowing function, as well as the elements of swallowing, in order to provide a rationale for speech therapy in patients with Parkinsonism manifesting dysphagia.
Eu Jeong Ko, Minji Chae, Sung-Rae Cho
doaj +1 more source
Progress on diagnosis and treatment of functional parkinsonism
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 Functional parkinsonism (FP) is a disorder caused by psychological factors rather than neurodegeneration. Functional parkinsonism has a great influence on patients' quality of life and daily function. However, due to overlapping with some of the symptoms
HUANG Pei, WANG Gang
doaj +1 more source
Diagnostic Evaluation of 99mTc-TRODAT-1 SPECT in Parkinsonism [PDF]
Journal of Research in Clinical Medicine, 2021 Background Parkinsonism as a group of movement disorders, exhibit similar clinical presentation. Therefore, clinically differentiating these diseases is difficult. We investigated the diagnostic value of 99m Tc-TRODAT-1 SPECT in this setting.
Zahra Babaei Aghdam +5 more
doaj +1 more source
Assessing bradykinesia in Parkinsonian disorders
Frontiers in Neurology, 2013 Objective: Bradykinesia is one of the clinical hallmarks of Parkinson’s disease (PD) and atypical Parkinsonian syndromes. Clinical ratings scales and technology based assessments have been developed to measure bradykinesia.
Gian ePal, Christopher G Goetz
doaj +1 more source
Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson's disease [PDF]
, 2015 Background Patients with advanced Parkinson's disease (PD) often present with axial symptoms, including postural- and gait difficulties that respond poorly to dopaminergic agents.
Pienaar, Ilse +28 more
core +1 more source