Results 31 to 40 of about 43,736 (227)

Single Photon Emission Tomography Imaging in Parkinsonian Disorders: A Review

Behavioural Neurology, 2000
Parkinsonian symptoms are associated with a number of neurodegenerative disorders, such as Parkinson’s disease, multiple system atrophy and progressive supranuclear palsy. Pathological evidence has shown clearly that these disorders are associated with a
Paul D. Acton, P. David Mozley
doaj   +1 more source

Clinical and Swallowing Characteristics Related With Respiratory Infection in Parkinsonism Patients [PDF]

Annals of Rehabilitation Medicine, 2023
Objective To investigate the clinical and swallowing characteristics related to respiratory infection in patients with parkinsonism. Methods One hundred and forty-two patients with parkinsonism who underwent videofluoroscopic swallowing studies (VFSS ...
Ji Su Jung, Heewon Jeon, Byung-Mo Oh, Han Gil Seo   +3 more
doaj   +1 more source

Pathophysiology and management of lower urinary tract dysfunction in parkinsonian Disorders: Update from the Neuro-Urology Promotion Committee of the ICS

Continence
Background and objective: Parkinson's disease and other Parkinsonian disorders, including multiple system atrophy, dementia with Lewy Bodies, progressive supranuclear palsy, and corticobasal degeneration, are commonly associated with lower urinary tract ...
Glenn T. Werneburg, Marcus J. Drake, Ryuji Sakakibara, Mikolaj Przydacz, Tatsuya Yamamoto, Sanjay Sinha   +5 more
doaj   +1 more source

Parkinsonian Syndromes in Motor Neuron Disease: A Clinical Study

Frontiers in Aging Neuroscience, 2022
BackgroundParkinsonian syndromes may rarely occur in motor neuron disease (MND). However, previous studies are heterogeneous and mostly case reports or small case series.
Jacopo Pasquini, Jacopo Pasquini, Jacopo Pasquini, Francesca Trogu, Francesca Trogu, Claudia Morelli, Barbara Poletti, Floriano Girotti, Silvia Peverelli, Alberto Brusati, Alberto Brusati, Antonia Ratti, Antonia Ratti, Andrea Ciammola, Vincenzo Silani, Vincenzo Silani, Nicola Ticozzi, Nicola Ticozzi   +17 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Genetic Sketch of Parkinson’s Disease in India

Annals of Indian Academy of Neurology
By the current estimates, India is likely to face an alarmingly high burden of Parkinson’s disease (PD) in the next two decades. Untangling the pathophysiology of PD through genetic research is the key to precision medicine and prevention strategies ...
Suvorit S Bhowmick, Soaham D Desai
doaj   +1 more source

Central Pain in Parkinson’s Disease: Behavioral and Cognitive Characteristics

Parkinson's Disease, 2021
Introduction. Pain is a major nonmotor symptom of Parkinson’s disease (PD), and central parkinsonian pain is the core feature of the putative Park pain subtype of PD.
N. Vila-Chã, S. Cavaco, A. Mendes, A. Gonçalves, I. Moreira, J. Fernandes, J. Damásio, L. F. Azevedo, J. M. Castro-Lopes   +8 more
doaj   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

PET Imaging of Neuro-Inflammation with Tracers Targeting the Translocator Protein (TSPO), a Systematic Review: From Bench to Bedside

Diagnostics, 2023
Parkinson’s disease is the second most common neurodegenerative disorder, affecting 2–3% of the population of patients >65 years. Although the standard diagnosis of PD is clinical, neuroimaging plays a key role in the evaluation of patients who present ...
Ferdinando Corica, Maria Silvia De Feo, Joana Gorica, Marko Magdi Abdou Sidrak, Miriam Conte, Luca Filippi, Orazio Schillaci, Giuseppe De Vincentis, Viviana Frantellizzi   +8 more
doaj   +1 more source