Results 31 to 40 of about 1,313,066 (193)

Parkinsonian beta oscillations in the external globus pallidus and their relationship with subthalamic nucleus activity [PDF]

open access: yes, 2008
Inappropriately synchronized beta (β) oscillations (15–30 Hz) in the subthalamic nucleus (STN) accompany movement difficulties in idiopathic Parkinson's disease (PD).
Bolam, JP   +12 more
core   +1 more source

Clinical and Swallowing Characteristics Related With Respiratory Infection in Parkinsonism Patients [PDF]

open access: yesAnnals of Rehabilitation Medicine, 2023
Objective To investigate the clinical and swallowing characteristics related to respiratory infection in patients with parkinsonism. Methods One hundred and forty-two patients with parkinsonism who underwent videofluoroscopic swallowing studies (VFSS ...
Ji Su Jung   +3 more
doaj   +1 more source

Pathophysiology and management of lower urinary tract dysfunction in parkinsonian Disorders: Update from the Neuro-Urology Promotion Committee of the ICS

open access: yesContinence
Background and objective: Parkinson's disease and other Parkinsonian disorders, including multiple system atrophy, dementia with Lewy Bodies, progressive supranuclear palsy, and corticobasal degeneration, are commonly associated with lower urinary tract ...
Glenn T. Werneburg   +5 more
doaj   +1 more source

Role of visuospatial cognition assessment in the diagnosis and research of atypical parkinsonian disorders

open access: yes, 2005
Visuospatial abilities play a pivotal role in our daily living. Indeed, our survival depends, to a great extent, on our ability to navigate sensory space.
MAGHERINI, Anna   +3 more
core   +1 more source

Parkinsonian Syndromes in Motor Neuron Disease: A Clinical Study

open access: yesFrontiers in Aging Neuroscience, 2022
BackgroundParkinsonian syndromes may rarely occur in motor neuron disease (MND). However, previous studies are heterogeneous and mostly case reports or small case series.
Jacopo Pasquini   +17 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Genetic Sketch of Parkinson’s Disease in India

open access: yesAnnals of Indian Academy of Neurology
By the current estimates, India is likely to face an alarmingly high burden of Parkinson’s disease (PD) in the next two decades. Untangling the pathophysiology of PD through genetic research is the key to precision medicine and prevention strategies ...
Suvorit S Bhowmick, Soaham D Desai
doaj   +1 more source

Central Pain in Parkinson’s Disease: Behavioral and Cognitive Characteristics

open access: yesParkinson's Disease, 2021
Introduction. Pain is a major nonmotor symptom of Parkinson’s disease (PD), and central parkinsonian pain is the core feature of the putative Park pain subtype of PD.
N. Vila-Chã   +8 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

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