Results 41 to 50 of about 42,265 (195)
Genetic Sketch of Parkinson’s Disease in India
Annals of Indian Academy of NeurologyBy the current estimates, India is likely to face an alarmingly high burden of Parkinson’s disease (PD) in the next two decades. Untangling the pathophysiology of PD through genetic research is the key to precision medicine and prevention strategies ...
Suvorit S Bhowmick, Soaham D Desai
doaj +1 more source
Affective symptoms in progressive supranuclear palsy
Journal of Geriatric Mental Health, 2014 Progressive supranuclear palsy is an unusual neurodegenerative disorder, which superficially resembles Parkinson′s disease, and the initial manifestations are characterized by depression, akinesia and mild cognitive impairment.
K S Shaji, K S Jyothi
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram +10 more
wiley +1 more source
Frontiers in Neurology, 2021 Parkinson disease (PD) is a complex neurodegenerative disorder, usually with multifactorial etiology. It is characterized by prominent movement disorders and non-motor symptoms.
Daniele Guadagnolo +7 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo +9 more
wiley +1 more source
Movement disorders in dengue encephalitis: a case report and literature review [PDF]
EncephalitisDengue is a mosquito-borne viral disease caused by the dengue virus (DENV). The clinical manifestations of DENV infection range from mild febrile illness to severe dengue shock syndrome and dengue hemorrhagic fever.
Pranjali Batra +4 more
doaj +1 more source
Probabilistic Lesion Mapping to Optimize Thalamotomy Targets for Focal Hand Dystonia
Annals of Neurology, EarlyView.Objective Focal hand dystonia (FHD) severely impairs task‐specific motor control, yet the optimal surgical target for stereotactic intervention remains uncertain. This study aimed to identify the precise thalamic lesion site associated with symptomatic improvement and to clarify its network connectivity. Methods We retrospectively analyzed 164 patients
Masahiko Nishitani +12 more
wiley +1 more source
The Disturbance of Gaze in Progressive Supranuclear Palsy (PSP): Implications for Pathogenesis
Frontiers in Neurology, 2010 Progressive supranuclear palsy (PSP) is a disease of later life that is currently regarded as a form of neurodegenerative tauopathy. Disturbance of gaze is a cardinal clinical feature of PSP that often helps clinicians to establish the diagnosis.
Athena L Chen +10 more
doaj +1 more source
Chronological Diagnostic Algorithm Predicting Neuropathology in Parkinsonism
Annals of Neurology, EarlyView.Objective Pre‐mortem diagnosis of parkinsonism is often challenging due to atypical presentations, overlapping syndromes, and co‐pathologies. This study aimed to develop a machine learning‐based algorithm predicting neuropathology in parkinsonism using chronological clinical presentations, which has previously been underexplored.
Daisuke Ono +5 more
wiley +1 more source
The effects that secondary parkinsonian syndromes have on health status
Journal of Education, Health and SportIntroduction and aim of work: The parkinsonian syndrome is a component of Parkinson's disease. A thorough neurological examination can detect symptoms belonging to the parkinsonian syndrome.
Dawid Kościołek +9 more
doaj +1 more source