Results 111 to 120 of about 450,934 (396)

Demographic and Clinical Profile of Patients with Parkinsonism in Northwestern Nigeria

Nigerian Journal of Medicine
Introduction: Parkinsonism is a disorder characterised by bradykinesia, rigidity, tremors and postural or gait abnormality of many aetiologies with idiopathic Parkinson’s disease (PD) topping the list of causes.
Halimat Hassan Amin, Salisu Abdullahi Balarabe, Abdullahi Ibrahim Augie, Kenechukwu Celsus Eze, Ochiaga Olisa, Farouk Kabir Umar   +5 more
doaj   +1 more source

Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies [PDF]

, 2016
Acknowledgments This work was supported by The Croatian Science Foundation grant No. IP-2014-09-9730 (“Tau protein hyperphosphorylation, aggregation, and trans-synaptic transfer in Alzheimer’s disease: cerebrospinal fluid analysis and assessment of ...
Babić Leko, Mirjana, Bažadona, Danira, Buée, Luc, de Silva, Rohan, Delalle, Ivana, Giovanni, Giuseppe Di, Harrington, Charles, Hof, Patrick R., Jovanov-Milošević, Nataša, Wischik, Claude, Wray, Selina, Šimić, Goran   +11 more
core   +3 more sources

SLC30A10 Is a Cell Surface-Localized Manganese Efflux Transporter, and Parkinsonism-Causing Mutations Block Its Intracellular Trafficking and Efflux Activity

Journal of Neuroscience, 2014
Manganese (Mn) is an essential metal, but elevated cellular levels are toxic and may lead to the development of an irreversible parkinsonian-like syndrome that has no treatment. Mn-induced parkinsonism generally occurs as a result of exposure to elevated
D. Leyva-Illades, Pan Chen, Charles E. Zogzas, S. Hutchens, J. Mercado, C. D. Swaim, R. Morrisett, A. Bowman, M. Aschner, Somshuvra Mukhopadhyay   +9 more
semanticscholar   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Learning Optimal Deep Projection of $^{18}$F-FDG PET Imaging for Early Differential Diagnosis of Parkinsonian Syndromes

, 2018
Several diseases of parkinsonian syndromes present similar symptoms at early stage and no objective widely used diagnostic methods have been approved until now.
AJ Hughes, CC Tang, D Eidelberg, D Zhang, F Gao, G Litjens, HI Suk, J Jiao, L Bi, L Zhou, R Li, S Fahn, S Lu, U Bagci, VK Ithapu, Y LeCun, Z Xu   +16 more
core   +1 more source

Balance differences in people with Parkinson disease with and without freezing of gait [PDF]

, 2015
Published in final edited form as: Gait Posture. 2015 September ; 42(3): 306–309. doi:10.1016/j.gaitpost.2015.06.007.BACKGROUND: Freezing of gait (FOG) is a relatively common and remarkably disabling impairment associated with Parkinson disease (PD).
Cavanaugh, James T., Dibble, Leland E., Duncan, Ryan P., Earhart, Gammon M., Ellis, Terry D., Ford, Matthew P., Foreman, K. Bo, Leddy, Abigail L.   +7 more
core   +1 more source

RAB39B Related Parkinsonism in an Italian Family: A Unique Use of Advanced Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Parkinson's disease (PD) is a neurodegenerative disorder that may sometimes be caused by deleterious genetic variants. Among them, RAB39B polymorphisms are known as rare causes of early‐onset PD associated with intellectual disability (Waisman's syndrome).
Caterina Del Regno, Giovanni Ermanis, Christian Lettieri, Andrea Bernardini, Gaia Pellitteri, Enrico Belgrado, Elena Betto, Gian Luigi Gigli, David De Monte, Marco Domenico Scanni, Marco Mucchiut, Giuseppe Damante, Mariarosaria Valente, Francesco Janes   +13 more
wiley   +1 more source

Exposure to disulfiram and incidence of parkinsonism

Journal of Occupational Medicine and Toxicology
Background Case reports implicate disulfiram treatment in causing parkinsonism, but these observations lack epidemiological confirmation. Aim of the present study was to estimate the risk of incident parkinsonism associated with disulfiram dispensing in ...
Angelo d’Errico, Elena Strippoli, Samuel M. Goldman, Paul D. Blanc   +3 more
doaj   +1 more source

Drug-induced parkinsonism in a patient with DiGeorge syndrome: a case report

Frontiers in Neuroscience
DiGeorge syndrome, also referred as 22q11.2 deletion syndrome is a multisystem disorder associated with an increased risk of early-onset parkinsonism.
Clancy Cerejo, Nicolas De Cleene, Gerald Walser, Atbin Djamshidian, Klaus Seppi, Beatrice Heim   +5 more
doaj   +1 more source

Ventricular Tachycardia during Cardiac Catheterization of Patient with Wolff-Parkinson-White Syndrome [PDF]

, 1950
Robert A. Bruce, Paul N. Yu, Frank W. Lovejoy, Marion E. McDowell, R. S. B. Pearson   +4 more
openalex   +1 more source