Results 121 to 130 of about 450,934 (396)

Anti-oxidants in Parkinson's disease therapy: a critical point of view [PDF]

, 2016
Parkinson's disease (PD) is a degenerative neurological syndrome, which is characterized by the preferential death of dopaminergic (DAergic) neurons in the SubstantiaNigra.
Beltramini, Mariano, Bisaglia, Marco, Bubacco, Luigi, Filograna, Roberta   +3 more
core   +2 more sources

The Sac1 Domain of SYNJ1 Identified Mutated in a Family with Early‐Onset Progressive Parkinsonism with Generalized Seizures

Human Mutation, 2013
This study aimed to elucidate the genetic causes underlying early‐onset Parkinsonism (EOP) in a consanguineous Iranian family. To attain this, homozygosity mapping and whole‐exome sequencing were performed. As a result, a homozygous mutation (c.773G>A; p.
Catharine E. Krebs, S. Karkheiran, James Powell, Mian Cao, Vladimir Makarov, H. Darvish, G. Di Paolo, R. Walker, G. Shahidi, J. Buxbaum, P. De Camilli, Zhenyu Yue, C. Paisán-Ruiz   +12 more
semanticscholar   +1 more source

Serum uric acid levels in older adults: Associations with clinical outcomes and implications for reference intervals in those aged 70 years and over

Arthritis Care &Research, Accepted Article.
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard, Cammie Tran, Hans G Schneider, Flavia M Cicuttini, Anita E Wluka, Ego Seeman, Johannes T Neumann, Md Nazmul Karim, Zhen Zhou, Sultana Monira Hussain, David P Q Clark, Daniel Clayton‐Chubb, Andrew M Tonkin, Lawrence J Beilin, Robyn L Woods, John J McNeil   +15 more
wiley   +1 more source

Treatment of Parkinsonism with a New Compound (B.S. 5930) [PDF]

, 1955
R. O. Gillhespy, A. Hall Ratcliffe
openalex   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source

Possible multiple system atrophy with predominant parkinsonism in a patient with chronic schizophrenia: a case report

BMC Psychiatry, 2018
Background Multiple system atrophy (MSA) is an adult-onset, rare, and progressive neurodegenerative disorder characterized by a varying combination of autonomic failure, cerebellar ataxia, and parkinsonism.
Hiroshi Komatsu, Masaaki Kato, Teiko Kinpara, Takashi Ono, Yoshihisa Kakuto   +4 more
doaj   +1 more source

An Unusual Case of Syphilitic Parkinsonism [PDF]

, 1953
Kevin Neill
openalex   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

Parkinsonism following ventriculoperitoneal shunt for treating hydrocephalus:clinical analysis on three cases

Chinese Journal of Contemporary Neurology and Neurosurgery, 2017
Objective To explore the clinical presentations, imaging features, probable pathogenesis and therapy of parkinsonism following ventriculoperitoneal shunt (VPS) in hydrocephalus.
Sheng-de LI, Lin WANG, Hong-zhi GUAN, Jun-ji WEI, Bin PENG, Xin-hua WAN   +5 more
doaj  

THE BRAIN-STEM LESIONS IN PARKINSONISM [PDF]

, 1953
J. G. Greenfield, Frances D. Bosanquet
openalex   +1 more source