Results 121 to 130 of about 435,882 (385)

The Sac1 Domain of SYNJ1 Identified Mutated in a Family with Early‐Onset Progressive Parkinsonism with Generalized Seizures

open access: yesHuman Mutation, 2013
This study aimed to elucidate the genetic causes underlying early‐onset Parkinsonism (EOP) in a consanguineous Iranian family. To attain this, homozygosity mapping and whole‐exome sequencing were performed. As a result, a homozygous mutation (c.773G>A; p.
Catharine E. Krebs   +12 more
semanticscholar   +1 more source

Immunomodulation With Local, Sustained Delivery of Pituitary Adenylate Cyclase Activating Polypeptide Results in Improved Functional Recovery in Stroke‐Injured Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho   +7 more
wiley   +1 more source

THE BRAIN-STEM LESIONS IN PARKINSONISM [PDF]

open access: bronze, 1953
J. G. Greenfield, Frances D. Bosanquet
openalex   +1 more source

Barriers to reporting non-motor symptoms to health-care providers in people with Parkinson's [PDF]

open access: yes, 2019
Background: Non-motor symptoms (NMS) are common in Parkinson's disease (PD) and cause significant distress. A high rate of non-declaration of NMS by patients to healthcare providers (HCP) means that many NMS remain untreated. Current understanding of the
Brown, R. G.   +5 more
core   +3 more sources

Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley   +1 more source

Parkinsonism following ventriculoperitoneal shunt for treating hydrocephalus:clinical analysis on three cases

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2017
Objective To explore the clinical presentations, imaging features, probable pathogenesis and therapy of parkinsonism following ventriculoperitoneal shunt (VPS) in hydrocephalus.
Sheng-de LI   +5 more
doaj  

Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies [PDF]

open access: yes, 2016
Acknowledgments This work was supported by The Croatian Science Foundation grant No. IP-2014-09-9730 (“Tau protein hyperphosphorylation, aggregation, and trans-synaptic transfer in Alzheimer’s disease: cerebrospinal fluid analysis and assessment of ...
Babić Leko, Mirjana   +11 more
core   +3 more sources

Miniaturized Wireless tDCS With Concentric Electrodes for Targeted Cortical Stimulation in Freely Moving Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a wireless and miniaturized concentric‐electrode tDCS (CE‐tDCS) system tailored for freely moving mice. The device enables focal and multi‐site cortical stimulation via a lightweight, Bluetooth‐controlled platform. By integrating local neuromodulation with real‐time behavioral analysis, the system provides a robust tool for ...
Minseok Kim   +5 more
wiley   +1 more source

Ventricular Tachycardia during Cardiac Catheterization of Patient with Wolff-Parkinson-White Syndrome [PDF]

open access: bronze, 1950
Robert A. Bruce   +4 more
openalex   +1 more source

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