Results 61 to 70 of about 74,974 (313)
Hematological profiles of patients with clinical parkinsonism and suspect parkinsonism.
, 2022 Hematological profiles of patients with clinical parkinsonism and suspect parkinsonism.
Hannah K. Hopkins (12065800) +2 more
core +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
FBX07-R498X mutation: Phenotypic variability from chorea to early onset parkinsonism within a family
, 2014 Objective: FBXO7 mutations (PARK 15), first reported in 2008, are among the monogenic causes of early-onset parkinsonism. Classically, PARK 15 was suggested to correspond to previously described pallido-pyramidal syndrome.
Hanagasi, Haşmet Ayhan +7 more
core +1 more source
Clinical features of patients with clinical parkinsonism and suspect parkinsonism.
, 2022 Clinical features of patients with clinical parkinsonism and suspect parkinsonism.
Hannah K. Hopkins (12065800) +2 more
core +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
BMC Neurology, 2019 Background Parkinsonism is a complex multifactorial neurodegenerative disorder, in which genetic and environmental risk factors may both play a role. Among environmental risk factors cocaine was earlier ambiguously linked to Parkinsonism.
Anett Illés +5 more
doaj +1 more source
Haplotype Analysis of Lrrk2 R1441h Carriers with Parkinsonism
, 2011 The Roc domain of the Lrrk2 protein harbors two pathogenic mutations which cause autosomal dominantparkinsonism (R1441C and R1441G). A third putatively pathogenic variant (R1441H) has been identified in four probands of diverse ethnicity with ...
Ross, Owen A.; Spanaki, Cleanthe; Griffith, Alida; Lin, Chin-Hsien; Kachergus, Jennifer; Haugarvoll, Kristoffer; Latsoudis, Helen; Plaitakis, Andreas; Ferreira, Joaquim J.; Sampaio, Cristina; Bonifati, Vincenzo; Wu, Ruey-Meei; Zabetian, Cyrus P.; Farrer, Matthew J. +1 more
core +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Bilateral parkinsonism in a patient with infarcts involving the unilateral basal ganglia
eNeurologicalSci, 2020 We describe a 61-year-old woman with bilateral parkinsonism caused by unilateral infarction limited to the territory of the lenticulostriate arteries.
Shiroh Miura +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source