Results 71 to 80 of about 435,882 (385)

Abnormal resting-state functional connectivity in progressive supranuclear palsy and corticobasal syndrome [PDF]

open access: yes, 2017
Background: Pathological and MRI-based evidence suggests that multiple brain structures are likely to be involved in functional disconnection between brain areas. Few studies have investigated resting-state functional connectivity (rsFC) in progressive
Berardelli, Alfredo   +9 more
core   +2 more sources

The MSA Atrophy Index (MSA‐AI): An Imaging Marker for Diagnosis and Clinical Progression in Multiple System Atrophy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo   +11 more
wiley   +1 more source

Dynamic interaction of genetic risk factors and cocaine abuse in the background of Parkinsonism – a case report

open access: yesBMC Neurology, 2019
Background Parkinsonism is a complex multifactorial neurodegenerative disorder, in which genetic and environmental risk factors may both play a role. Among environmental risk factors cocaine was earlier ambiguously linked to Parkinsonism.
Anett Illés   +5 more
doaj   +1 more source

血管性帕金森综合征鉴别诊断的影像学研究进展 Advances of Imaging in the Differential Diagnosis of Vascular Parkinsonism

open access: yesZhongguo cuzhong zazhi, 2023
血管性帕金森综合征(vascular parkinsonism,VP)是临床上常见的继发性帕金森综合征,目前VP临床诊断和鉴别诊断的准确率较低,影响其临床治疗和预后。在临床实践中,影像学常用于VP的诊断。近年来多模态MRI和分子影像成像及分析技术等影像学技术的进展为提高VP的诊断和鉴别诊断准确率提供了客观手段。本文就前沿影像学技术在VP与原发性帕金森病以及其他非典型帕金森综合征鉴别诊断领域的研究进展进行综述,以期为VP的诊断和鉴别诊断提供新的思路。 Abstract: Vascular ...
张冬玲,吴涛
doaj   +1 more source

Cerebellum: an explanation for dystonia? [PDF]

open access: yes, 2017
Dystonia is a movement disorder that is characterized by involuntary muscle contractions, abnormal movements and postures, as well as by non-motor symptoms, and is due to abnormalities in different brain areas.
Berardelli, Alfredo, Bologna, Matteo
core   +1 more source

Association Between Gadolinium Contrast Exposure and the Risk of Parkinsonism.

open access: yesJournal of the American Medical Association (JAMA), 2016
initial MRI was of the brain or spinal cord and those with prior parkinsonism or neurosurgery were excluded. Patients who were exposed to gadolinium-enhanced MRIs (modeled as a time-varying, cumulative count variable) were compared with patients who ...
B. Welk   +6 more
semanticscholar   +1 more source

Parkinson Matters

open access: yesJournal of Parkinson’s Disease, 2018
Recent epidemiological observations have drawn attention to the rapid rise in the burden caused by Parkinson’s disease over the past years, emphasizing that Parkinson’s disease is a matter of serious concern for our future generations. A recent report by Public Health England corroborates this message, by providing new insight on trends in deaths ...
Darweesh, S.K.L.   +6 more
openaire   +5 more sources

Fixel‐Based Analysis of Diffusion Imaging as a Quantitative Marker of Disease State in Spinocerebellar Ataxia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCAs) are a group of genetically heterogeneous neurodegenerative diseases causing progressive deterioration and reduced quality of life. Therapeutic advances have been limited by a lack of sensitive anatomic, functional, or diffusion imaging‐based biomarkers.
David J. Arpin   +11 more
wiley   +1 more source

Metoclopramide Neurological Side Effects Screening; A Pharmacovigilence Study in Romanian Community Pharmacies [PDF]

open access: yes, 2015
Background. Metoclopramide is a pharmacological agent frequently used in therapy against nausea and vomiting that can occur in indigestion, motion sickness, gastric ulcer, pyloric spasm and after surgery as a side effect of some anesthetics.
Junghină, Adrian   +4 more
core   +3 more sources

Neurotoxicity [PDF]

open access: yes, 2014
Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust   +15 more
core   +2 more sources

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