Results 71 to 80 of about 103,898 (266)

Park the Parking

JCO Oncology Practice, 2020
Naveen, Premnath, Udhayvir Singh, Grewal, Arjun, Gupta   +2 more
openaire   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Avian biodiversity in the urban green spaces of Paris: higher bird species richness in larger parks and park centers

Avian Conservation and Ecology
Diverse anthropogenic threats drive bird population declines, especially for species living in urban areas. Through studies of avian species richness in urban green spaces, i.e., the parks, gardens, and cemeteries of modern cities, we gain a deeper ...
Daniel J. Mennill, Stephanie M. Gamboa, Emily M. Bolger, Madison I. Bygrove, Micaela Carlini, Katie A. Cesca, Hannah L. Drew, Natalie A. Emerick, Adam Gaisinsky, Reese M. Miller, Linda Nguyen, Liam D. O'Leary, Sona Regonda, Danielle N. Robinson, Emily Tessier, Stephanie M. Doucet   +15 more
doaj   +1 more source

From the heap to the park – reclamation and adaptation of degraded urban areas for recreational functions in Poland

Przegląd Naukowy Inżynieria i Kształtowanie Środowiska, 2019
The article covers the issue of land reclamation of two degraded urban areas: Silesia Park (Chorzów city, Southern Poland) and Górka Rogowska Park (Łódź city, Central Poland). The research raises the subject of vegetation condition, plant succession, and
Jan Łukaszkiewicz, Beata Fortuna-Antoszkiewicz, Andrzej Długoński, Piotr Wiśniewski   +3 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Economic Value of Florida Water Resources: Contributions of Tourism and Recreation to the Economy

EDIS, 2020
This paper is a part of the EDIS series “Economic Value of Florida Water Resources” and it presents results from economic studies examining benefits from water-based recreation in Florida. Our special focus is freshwater-based recreation.
Tatiana Borisova, Kurt Oehlbeck, Xiang Bi, Tara Wade, Alan Hodges, Kelly Grogan, Fe Hei   +6 more
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Conservancies in Coastal British Columbia: A New Approach to Protected Areas in the Traditional Territories of First Nations

Conservation & Society, 2015
In British Columbia (BC), Canada, the provincial government and First Nations have recently created an innovative new form of collaboratively managed protected area.
Jessica Stronghill, Murray B Rutherford, Wolfgang Haider   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source