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The Efficacy of Combination Therapy With SWTX Capsule and Paroxetine for Depression: A Randomized Controlled Trial [PDF]

open access: yesHealth Science Reports
Background and Aims Depression, a leading global cause of disease burden, often shows limited response and notable adverse reactions to existing antidepressants.
Yanting Fan   +3 more
doaj   +2 more sources

Paroxetine-induced black hairy tongue and necrotizing sialometaplasia: a case report [PDF]

open access: yesJournal of Medical Case Reports
Background Black hairy tongue, also known as lingua villosa nigra, is a reversible benign disease on the dorsum of the tongue characterized by elongated and hypertrophied filiform lingual papillae.
Zhuang Ying Lee, Manjit Dhillon
doaj   +2 more sources

Peripheral Edema Related to Paroxetine Discontinuation: A Case Report

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Paroxetine is a selective serotonin reuptake inhibitor (SSRI), with antidepressant and anxiolytic characteristics. In association with paroxetine cessation, certain side effects can be observed frequently, including dizziness, vertigo, nausea, vomiting,
Osman Mermi, Murad Atmaca
doaj   +1 more source

No interaction between plasma IL-6 and MHPG in major depression treated with paroxetine

open access: yesPsychiatry Research Communications, 2022
We investigated the plasma levels of MHPG, a metabolite of noradrenaline or IL-6, and the clinical response to paroxetine in major depression (MD). Twenty-eight patients who met the MD criteria as per DSM-5 were enrolled in this study (age 42 ​± ​8 years;
Reiji Yoshimura   +2 more
doaj   +1 more source

Pharmacokinetics of immediate and sustained-release formulations of paroxetine: Population pharmacokinetic approach to guide paroxetine personalized therapy in chinese psychotic patients

open access: yesFrontiers in Pharmacology, 2022
Paroxetine is one of the most potent selective serotonin reuptake inhibitors (SSRIs) approved for treating depression, panic disorder, and obsessive-compulsive disorder.
Xiao-lin Li   +15 more
doaj   +1 more source

Distribution of Plasma One-Carbon Metabolism Factors and Amino Acids Profile in Depression State Treated with Paroxetine: A Model Study [PDF]

open access: yesCell Journal, 2023
Objective: Stress may have an important role in the origin and progress of depression and can impair metabolichomeostasis. The one-carbon cycle (1-CC) metabolism and amino acid (AA) profile are some of the consequencesrelated to stress. In this study, we
Reyhaneh Aghajani   +5 more
doaj   +1 more source

Paroxetine can improve primary visual cortex activity in a high-risk mouse model of schizophrenia

open access: yesBiotechnology & Biotechnological Equipment, 2020
Visual cortex functional deficits can be observed in schizophrenia patients and in individuals at high risk of schizophrenia. However, to date, few studies have investigated methods to improve these functional deficits.
Xinying Chen   +11 more
doaj   +1 more source

Paroxetine-induced galactorrhea

open access: yesEuropean Psychiatry, 2022
Introduction Antidepressant-induced galactorrhea and increases in prolactin levels have been sporadically reported among SSRI-related side effects. Objectives Current rapport presents a case of 39 y.o.
S. Petrykiv, M. Arts, L. De Jonge
doaj   +1 more source

Anti-proliferative effects of paroxetine alone or in combination with sorafenib in HepG2 cells

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2023
Hepatocellular carcinoma (HCC) is a common cause of cancer-related death. Sorafenib is the first approved drug for the treatment of advanced HCC. Depression is frequent in cancer patients.
Yaprak Donmez Cakil   +4 more
doaj   +1 more source

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