Results 31 to 40 of about 39,514 (227)

Paroxetine is Pro-inflammatory in Human Brain Microvascular Endothelial Cells [PDF]

, 2020
BACKGROUND: Paroxetine is an antidepressant that is widely used. However, Paroxetine possesses anticholinergic properties which may contribute to cognitive decline in older adults.
Hashimi, Syeda, Hassan, Omar, Odeniyi, Bukola, Patel, Sulay   +3 more
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Antidepressants in pregnancy and breastfeeding [PDF]

, 2007
Copyright © 2007 Australian Prescriber Reproduced with permission from Australian Prescriber The document attached has been archived with permission from the publisher/copyright holder.Maternal depression and anxiety during pregnancy and the early years ...
Sved-Williams, A.
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Paroxetine ameliorates prodromal emotional dysfunction and late-onset memory deficit in Alzheimer’s disease mice

Translational Neurodegeneration, 2020
Background Neuropsychiatric symptoms (NPS) such as depression, anxiety, apathy, and irritability occur in prodromal phases of clinical Alzheimer’s disease (AD), which might be an increased risk for later developing AD.
Peng-Hui Ai, Si Chen, Xian-Dong Liu, Xiao-Na Zhu, Yuan-Bo Pan, Dong-Fu Feng, Shengdi Chen, Nan-Jie Xu, Suya Sun   +8 more
doaj   +1 more source

The FDA “black box” warning on antidepressant suicide risk in young adults: More harm than benefits? [PDF]

, 2019
The decision made in the year 2004 by the U.S. Food and Drug Administration (FDA) to require a boxed warning on antidepressants regarding the risk of suicidality in young adults still represents a matter of controversy.
Anastasia A., Carano A., De Berardis D., Di Giannantonio M., Fornaro M., Martinotti G., Natale S. D., Olivieri L., Orsolini L., Perna G., Rapini G., Valchera A., Vellante F.   +12 more
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Nefazodone in psychotic unipolar and bipolar depression: A retrospective chart analysis and open prospective study on its efficacy and safety versus combined treatment with amitriptyline and haloperidol [PDF]

, 2002
Although atypical antipsychotics are on the rise, traditional treatment of psychotic (or delusional) depression mostly includes the addition of classical antipsychotics to antidepressants. As there are only few data supporting this approach compared with
Born, Christoph, Grunze, Heinz, Marcuse, Alain, Schaerer, Lars O., Walden, Jörg   +4 more
core   +1 more source

Treatment of pruritus in a palliative care patient with low-dose paroxetine: a case report

Journal of Medical Case Reports, 2017
Background Pruritus is a distressing symptom seen in palliative care. There is limited high-quality evidence of pharmaceutical treatments for pruritus in palliative care, including the use of paroxetine.
Roni Y. Kraut
doaj   +1 more source

Paroxetine and Mortality in Heart Failure: A Retrospective Cohort Study

Frontiers in Cardiovascular Medicine, 2022
IntroductionParoxetine is a GRK2 inhibitor that has been widely used to treat depression and anxiety over the last few decades. The inhibition of GRK2 has been studied extensively in vivo; however, evidence of its impact on heart failure remains scarce ...
Hongxuan Xu, Hongxuan Xu, Lingbing Meng, Lingbing Meng, Huanyu Long, Yueping Shi, Yunqing Liu, Yunqing Liu, Li Wang, Li Wang, Deping Liu, Deping Liu, Deping Liu   +12 more
doaj   +1 more source

Interventions for treating depression after stroke [PDF]

, 2008
Background: Depression is an important consequence of stroke that impacts on recovery yet is often not detected or inadequately treated. This is an update of a Cochrane review first published in 2004.
Agnoli, Ahrens, Aizawa, American Psychiatric Association, American Psychiatric Association, Andersen, Andersen, Andersen, Andersen, Andersen, Anderson, Annonymous, Astrom, Atarashi, Balunov, Bao, Battaglia, Battaglia, Bautz-Holter, Beck, Berrol, Burvill, Burvill, Burvill, Carson, Casella, Chan, Chen, Chen, Chen, Chen, Cheng, Cheng, Choi-Kwon, Choi-Kwon, Christie, Corr, Corr, Cui, Cullum, Davis, Deans, Dennis, Dennis, Desrosiers, Deutsch, Dong, Drummond, Du, Duval, Ebrahim, Evans, Evans, Feng, Feng, Fengqi, Folstein, Fruehwald, FX Project for Phase III Study, Gekht, Gekht, Gill, Goldberg, Gompertz, Gonzalez-Torrecillas, Green, Guan, Guan, Hackett, Hackett, Hackett, Hackett, Hamilton, He, He, He, Herrmann, Hollis, Hong, House, House, House, House, Hu, Hu, Huang, Huang, Hui, Hunt, Ji, Jia, Jiang, Jiang, Johnson, Johnson, Jongbloed, Jorge, Joubert, Juby, Katona, Katz, Keller, Kendall, Kimura, Kirsch, Kumar, Kwon, Lai, Lai, Laska, Latow, Lauritzen, Leff, Lehmann, Leijon, Li, Li, Li, Li, Li, Li, Li, Li, Li, Li, Liang, Liang, Lima, Lin, Lincoln, Lincoln, Lipsey, Lipsey, Liu, Liu, Liu, Liu, Liu, Lu, Mahoney, Mant, Mant, Martucci, Marui, McCusker, Meara, Meng, Miao, Min, Min, Mittmann, Miyai, Moher, Montgomery, Morris, Murray, Murray, Niedermaier, Niedermaier, Nir, Normand, Nour, Ohtomo, Ohtomo, Ostwald, Otomo, Parikh, Pearson, Ponzio, Rampello, Rampello, Rankin, Reding, Ricauda, Ricauda, Roberts, Robinson, Rodgers, Rudd, Ruddell, Rønning, Sandberg, Shan, Sharpe, Sinyor, Sivenius, Smedley, Smith, Snow, Song, Stenager, Su, Su, Sulch, Sulch, Suskin, Tan, Taragano, Taragano, Thomas, Towle, Towle, Towle, Turner-Stokes, Verhagen, Wade, Wade, Walker-Batson, Walsh, Wang, Wang, Wang, Wang, Ware, Watkins, Werner, Wheeler, Wiart, Wiart, Wilkinson, Williams, Wolfe, Wu, Xia, Xiaoying, Xie, Xie, Xie, Xing, Xu, Yang, Ye, Yi, Yoneyama, You, Young, Yu, Yu, Yu, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhao, Zhao, Zhao, Zhou, Zhou B. Xiao, Zhu, Zifko, Zigmond, Zimmerman   +254 more
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The Different Roles of 5-HT2 and 5-HT3 Receptors on Antinociceptive Effect of Paroxetine in Chemical Stimuli in Mice

Journal of Pharmacological Sciences, 2005
Serotonin (5-HT) is known to be an important mediator in pain modulation. Some centrally acting agents, like selective serotonin reuptake inhibitors (SSRIs), modulate pain.
Murat Kesim, Erdem N. Duman, Mine Kadioglu, Ersin Yaris, Nuri I. Kalyoncu, Nesrin Erciyes   +5 more
doaj   +1 more source

Depression and/or PTSD Comorbidity Affects Response to Antidepressants in Those With Alcohol Use Disorder

Frontiers in Psychiatry, 2022
Objective: Depression and post-traumatic stress disorder (PTSD) highly co-occur with alcohol use disorder (AUD). The comparative effects of noradrenergic vs.
Peter J. Na, Peter J. Na, Elizabeth Ralevski, Elizabeth Ralevski, Oluwole Jegede, Aaron Wolfgang, Ismene L. Petrakis, Ismene L. Petrakis   +7 more
doaj   +1 more source