Results 51 to 60 of about 25,024 (228)
Artificial Cells, Nanomedicine, and Biotechnology, 2023 Paroxetine is not suitable for oral administration due to its extensive first-pass metabolism, thus resulting in less bioavailability. This study aimed to prepare novel paroxetine-loaded solid lipid nanoparticles (SLNs) based sustained-release ...
Fahad Pervaiz +6 more
doaj +1 more source
Drug Testing and Analysis, EarlyView.A total of 2121 used syringes were analyzed in Athens, Thessaloniki, and Patras between 2022 and 2024. Distinct drug‐use patterns were observed across the three cities. Benzodiazepines, pregabalin, methadone, and fentanyl were increasingly detected in 2024.
Christina Matiaki +10 more
wiley +1 more source
Journal of Pharmacological Sciences, 2004 Antidepressant drugs, especially tricyclics have been widely used in the treatment of chronic pain, but not in acute pain. Because of numerous undesirable side effects, the selective serotonin reuptake inhibitors (SSRIs), with their favorable side effect
Erdem N. Duman +5 more
doaj +1 more source
Translational Psychiatry, 2021 Major depressive disorder is the most prevalent mental illness worldwide, still its pharmacological treatment is limited by various challenges, such as the large heterogeneity in treatment response and the lack of insight into the neurobiological ...
David P. Herzog +11 more
doaj +1 more source
European Eating Disorders Review, EarlyView.ABSTRACT Objective To investigate real‐world psychopharmacological prescribing patterns among Italian adolescents with anorexia nervosa (AN) compared with psychiatric controls without eating disorders, and to examine whether AN diagnosis independently predicts medication use after accounting for psychiatric comorbidities.
Marika Orlandi +5 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Chiara Benedetto +8 more
wiley +1 more source
, 2016 Two Candida antarctica lipases catalyze the enantioselective acylation of N-substituted trans-4-(4‘-fluorophenyl)-3-hydroxymethylpiperidines in organic solvents. These two lipases show opposite stereochemical preference in these processes.
Gonzalo de Gonzalo (2310898) +4 more
core +1 more source
Anxiety disorder and anxiolytic pharmacotherapy during pregnancy: The impact on pregnancy outcomes
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective This study determines the contributions of anxiety disorder and anxiolytic pharmacotherapy on perinatal outcomes and examines prescribing trends during pregnancy. Methods A retrospective cohort study was conducted at a single tertiary medical center between 2013 and 2024.
Sher Goaz Melet +5 more
wiley +1 more source
Basic and Clinical Neuroscience, 2012 Introduction: Although the effectiveness of paroxetine and Attention Modification Program has been studied separately in treating social anxiety disorder, there has been no research comparing them according to the literature. The aim of this study was to
Aliasghar Asgharnejad Farid +3 more
doaj +2 more sources
Journal of Traumatic Stress, EarlyView.Abstract Posttraumatic stress disorder (PTSD) disrupts individual well‐being and relationship health, particularly among veteran/military couples with heightened risks due to deployment, family reintegration, and traumatic stress. Although cognitive‐behavioral conjoint therapy (CBCT) and brief CBCT (bCBCT) have demonstrated strong efficacy in reducing ...
Leslie A. Morland +11 more
wiley +1 more source