Results 71 to 80 of about 25,024 (228)

How common is alcohol use disorder in posttraumatic stress disorder? A systematic review, meta‐analysis, and moderator analysis

The American Journal on Addictions, EarlyView.
Abstract Background and Objectives Comorbidity between posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) complicates care, yet reported prevalence varies widely across settings and methods. We estimated AUD prevalence among adults with PTSD and identified sources of variability.
Maria Olivia Pozzolo Pedro, Manoela Pozzolo Pedro, Gabriella Zimmer Monteiro, Valquíria Custodio Klaumann, Priscila Dib Gonçalves, Silvia S. Martins, João Maurício Castaldelli‐Maia   +6 more
wiley   +1 more source

Critical appraisal of paroxetine for the treatment of vasomotor symptoms

, 2015
Dana G Carroll,1,2 Katelin M Lisenby,1,2 Tracy L Carter3 1Department of Pharmacy Practice, Harrison School of Pharmacy, Auburn University, Auburn, AL, USA; 2Department of Family Medicine, College of Community Health Sciences, University of Alabama ...
Lisenby KM, Carroll DG, Carter TL
core  

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

The effects of paroxetine on lifespan, feeding behavior, and other physiological parameters in the nematode C. elegans under a modified bacterial diet

Experimental Gerontology
Paroxetine, a widely prescribed selective serotonin reuptake inhibitor (SSRI), is known for its metabolic side effects, yet its long-term physiological impacts remain incompletely understood. This study investigated the effects of paroxetine on lifespan,
Abdullah M. Almotayri, Ali H. Alghamdi, K. ELSHERBINY, Ali A. Hroobi, Nourah M. Almimoni, Hussam A. Althagafi, Tariq Saeed Alghamdi, Fatehia N. Gharsan, Mariam S. Alghamdi, Abdullah A.A. Alghamdi   +9 more
doaj   +1 more source

Gold‐standard evidence and best practice guidance for menstrual cycle‐informed clinical care: An overview for clinicians

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert, Louise N. Nolan, Katja M. Schmalenberger   +2 more
wiley   +1 more source

Paroxetine in the Treatment of Post Traumatic Stress Disorder: Our Experiences

Biomolecules & Biomedicine, 2008
Posttraumatic stress disorder can develop after individual’s exposure or witnessing of life threatening events. It is characterized by three clusters of symptoms. The course of PTSD is often chronic and impedes individual’s functioning.
Abdulah Kučukalić, Alma Bravo-Mehmedbašić, Alma Džubur-Kulenović   +2 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

Escitalopram versus paroxetine controlled release in major depressive disorder: a randomized trial

, 2017
Taro Kishi,1 Yuki Matsuda,1 Shinji Matsunaga,1 Masatsugu Moriwaki,1,2 Yoichiro Otake,2 Kaku Akamatsu,3 Tomo Okochi,4 Shigeki Hirano,4 Toshihiko Funahashi,5 Momoko Okuda,6 Hideaki Tabuse,6 Kiyoshi Fujita,2 Nakao Iwata1 1Department of Psychiatry, Fujita ...
Okochi T, Okuda M, Otake Y, Iwata N, Funahashi T, Fujita K, Akamatsu K, Kishi T, Matsuda Y, Hirano S, Tabuse H, Matsunaga S, Moriwaki M   +12 more
core  

Remapping the Synthetic Landscape of α‐Tertiary Alkylamines via Dual‐Functional Catechol

Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.
A three‐component assembly strategy has been developed for the modular synthesis of hindered α‐tertiary aliphatic amines from readily available precursors through unlocking the dual role of catechol. The practicality of this methodology has been demonstrated in over 90 examples, including compounds that are otherwise difficult to access, along with ...
Chen‐Yan Cai, Yuzuru Kanda, Tian Qin
wiley   +2 more sources