Results 81 to 90 of about 25,024 (228)
Hemodialysis International, EarlyView.ABSTRACT Introduction End stage kidney disease (ESKD) is associated with a high prevalence of depression and anxiety, arising from both biological factors and the psychosocial burden of chronic dialysis care. Approximately 25%–30% of dialysis patients experience clinically significant depressive symptoms when assessed by structured clinical interview ...
Kunal Malhotra +2 more
wiley +1 more source
Frontiers in MedicineIntroductionThis clinical trial is designed to explore the efficacy of paroxetine and gabapentin in alleviating functional gastrointestinal symptoms, anxiety, depression, and quality of life in patients with ulcerative colitis during the remission stage ...
Farahnaz Safaei +4 more
doaj +1 more source
Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis
International Journal of Dermatology, EarlyView.Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller +11 more
wiley +1 more source
, 2018 Jian-wei Chen, Shu-qin Xie Department of Nephrology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China Objective: Depressive and anxiety symptoms could affect the quality of life and prognostic outcomes in chronic kidney ...
Chen JW, Xie SQ
core
The Antidepressant Paroxetine Reduces the Cardiac Sodium Current
, 2023 A considerable amount of literature has been published on antidepressants and cardiac ion channel dysfunction. The antidepressant paroxetine has been associated with Brugada syndrome and long QT syndrome, albeit on the basis of conflicting findings.
Arie O. Verkerk +2 more
core +1 more source
Internal Medicine Journal, EarlyView.Abstract Background Pharmacogenomic‐guided medication management optimises drug therapy to enhance patient outcomes. Despite clinical utility, implementation in Australia remains limited, partly due to the lack of clear and consistent guidance. Aim This study evaluated the presence and consistency of pharmacogenomic testing indication categories and ...
Ruby Soueid +4 more
wiley +1 more source
Antidepressants inhibit P2X4 receptor function: a possible involvement in neuropathic pain relief
Molecular Pain, 2009 Background Neuropathic pain is characterized by pain hypersensitivity to innocuous stimuli (tactile allodynia) that is nearly always resistant to known treatments such as non-steroidal anti-inflammatory drugs or even opioids.
Tozaki-Saitoh Hidetoshi +5 more
doaj +1 more source
Journal of the American Geriatrics Society, EarlyView.ABSTRACT Background Little is known about substitution of alternative medications in the context of deprescribing. The objectives were to: (1) determine the frequency of medication substitutions among those who discontinued a central nervous system (CNS)‐active medication, and (2) characterize substitutions as potentially inappropriate (as per the 2023
Shelly L. Gray +6 more
wiley +1 more source
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont +5 more
wiley +1 more source
Toxic hepatitis associated with paroxetine
, 2005 Hepatotoxicity is a rare complication of paroxetine, a selective serotonin reuptake inhibitor. Regarded as safe in therapeutic use, there have been reports of cases of severe hepatic dysfunction with gross elevations of transaminase levels that may be ...
Tankurt, E +6 more
core +1 more source