Results 81 to 90 of about 39,514 (227)
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont +5 more
wiley +1 more source
Triggers for atrial fibrillation. the role of anxiety [PDF]
, 2019 Atrial fibrillation (AF) is the most widely recognized arrhythmia. Systemic arterial hypertension, diabetes, obesity, heart failure, and valvular heart diseases are major risk factors for the onset and progression of AF.
Ceccacci, Andrea +10 more
core +1 more source
Migraine and Restless Legs Syndrome: A Meta‐Analysis
Journal of Sleep Research, EarlyView.ABSTRACT Restless legs syndrome is a sensorimotor disorder of sleep/wake regulation that frequently coexists with migraine, affecting patients' quality of life. This study aimed to estimate the prevalence of restless legs syndrome in individuals with migraine and to explore the associated clinical, demographic and behavioural aspects.
Florindo d'Onofrio +8 more
wiley +1 more source
Photochemistry and Photobiology, EarlyView.In this model, ROS generated by UVB result in PAFR agonists acting upon the PAFR resulting in MVP generation release via the enzyme aSMase. In photosensitivity, there are increased ROS, resulting in augmented PAF agonists and increased MVP release. This process can be blocked by aSMase inhibitors.
Risha Annamraju +13 more
wiley +1 more source
Experimental GerontologyParoxetine, a widely prescribed selective serotonin reuptake inhibitor (SSRI), is known for its metabolic side effects, yet its long-term physiological impacts remain incompletely understood. This study investigated the effects of paroxetine on lifespan,
Abdullah M. Almotayri +9 more
doaj +1 more source
Paroxetine in the Treatment of Post Traumatic Stress Disorder: Our Experiences
Biomolecules & Biomedicine, 2008 Posttraumatic stress disorder can develop after individual’s exposure or witnessing of life threatening events. It is characterized by three clusters of symptoms. The course of PTSD is often chronic and impedes individual’s functioning.
Abdulah Kučukalić +2 more
doaj +1 more source
Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone [PDF]
, 2018 Purpose: The main metabolic pathways of oxycodone, a potent opioid analgetic, are N-demethylation (CYP3A4) to inactive noroxycodone and O-demethylation (CYP2D6) to active oxymorphone.
Drewe, Jürgen +5 more
core
Myoclonus-dystonia : distinctive motor and non-motor phenotype from other dystonia syndromes [PDF]
, 2019 Background: myoclonus-dystonia (M-D) due to a pathogenic variant of SGCE is an autosomal dominant inherited movement disorder. Apart from motor symptoms, psychiatric disorders are highly prevalent in patients with MD.
Bartels, Anna L. +8 more
core +2 more sources
The Journal of Physiology, EarlyView.Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite +9 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato +3 more
wiley +1 more source