Results 101 to 110 of about 25,024 (228)

Paroxetine increases steady-state concentrations of (R)-methadone in CYP2D6 extensive but not poor metabolizers

, 2002
Steady-state blood concentrations of (R)- methadone (i.e., the active form), (S)-methadone, and (R,S)-methadone were measured before and after introduction of paroxetine 20 mg/day during a mean period of 12 days in 10 addict patients in methadone ...
Begré, S, von Bardeleben, U, Cosendai-Savary, L, Golay, KP, Eap, CB, Baumann, P, Jaquet-Rochat, S, Kosel, M, Ladewig, D   +8 more
core   +1 more source

Comparison of paroxetine and agomelatine in depressed type 2 diabetes mellitus patients: a double-blind, randomized, clinical trial

, 2015
Ruiying Kang,1 Yan He,1 Yuxiang Yan,1 Zhiwu Li,2 Yeqing Wu,3 Xiaojuan Guo,4 Zhigang Liang,5 Jun Jiang2 1Department of Epidemiology and Biostatics, School of Public Health, Capital Medical University, Beijing, People’s Republic of China; 2Fengtai ...
Yan YX, Jiang J, He Y, Wu YQ, Guo XJ, Liang ZG, Kang RY, Li ZW   +7 more
core  

Mean prolactin levels before PEG among patients taking escitalopram, paroxetine, and sertraline (ESC; escitalopram, PRX; paroxetine, SERT; sertraline).

, 2013
Mean prolactin levels before PEG among patients taking escitalopram, paroxetine, and sertraline (ESC; escitalopram, PRX; paroxetine, SERT; sertraline).
Sollip Kim (491807), Young-Min Park (400821)   +1 more
core   +1 more source

National patterns of paroxetine use among US Medicare patients from 2015–2020

Frontiers in Psychiatry
IntroductionParoxetine is an older “selective” serotonin reuptake inhibitor (SSRI) that is notable for its lack of selectivity, resulting in an anticholinergic adverse-effect profile, especially among older adults (65+).MethodsParoxetine prescription ...
Luke R. Cavanah, Jessica L. Goldhirsh, Leighton Y. Huey, Leighton Y. Huey, Brian J. Piper, Brian J. Piper   +5 more
doaj   +1 more source

Culture‐Negative Septic Pulmonary Embolism Secondary to Lower‐Limb Cellulitis Following Recent Dengue Fever Complicated by Hydropneumothorax: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Secondary bacterial infection and septic pulmonary embolism should be considered in patients recovering from dengue fever who develop focal soft‐tissue infection, respiratory symptoms, or markedly elevated inflammatory markers. Characteristic radiological findings may establish the diagnosis even when blood cultures are negative and infective ...
Faiza Arif, Mariyah Saqib Qureshi, Sajjad Khan, Malaika Usman, Umama Rehman, Aiyna Usman, Bilal Wazir Khan, Kashif Yousaf   +7 more
wiley   +1 more source

Superiority of escitalopram to paroxetine in the treatment of depression

, 2009
Post-hoc pooled analysis of data from two 6-month randomised controlled trials in patients with major depressive disorder (MDD) revealed superior efficacy and tolerability of escitalopram when compared with paroxetine.
Kasper, Siegfried, Boulenger, Jean-Philippe, Lönn, Sara Larsson, Baldwin, David S.   +3 more
core   +1 more source

Tryptophan metabolism in colorectal cancer: From mechanistic insights to novel therapeutic strategies

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Tryptophan metabolism modulates CRC via three microbiota‐regulated pathways with distinct dual‐mode effects. The kynurenine pathway provides biomarkers, serotonin pathway supports SSRI‐combined immunotherapy, indole pathway yields immunostimulatory metabolites, collectively offering translational prospects.
Ran Wang, Wenke Shen, Ping Yang, Dongxue Yang, Yuepeng Cao, Yuping Zhou   +5 more
wiley   +1 more source

Paroxetine binding to the rat norepinephrine transporter in vivo

, 2000
Background: The norepinephrine transporter (NET)/uptake site is an antidepressant-sensitive transporter located on plasma membranes of noradrenergic neurons and other specialized cells that remove norepinephrine (NE) from the synapse to terminate the ...
Owens, Michael J, Charles B Nemeroff, David L Knight, Nemeroff, Charles B, Knight, David L, Michael J Owens   +5 more
core   +1 more source

Paroxetine is Pro-inflammatory in Human Brain Microvascular Endothelial Cells [PDF]

, 2020
BACKGROUND: Paroxetine is an antidepressant that is widely used. However, Paroxetine possesses anticholinergic properties which may contribute to cognitive decline in older adults.
Hashimi, Syeda, Patel, Sulay, Odeniyi, Bukola, Hassan, Omar   +3 more
core  

The selective serotonin reuptake inhibitor paroxetine improves right ventricular systolic function in experimental pulmonary hypertension

Journal of Molecular and Cellular Cardiology Plus
Background: Pulmonary hypertension (PH) often leads to right ventricle (RV) failure, a significant cause of morbidity and mortality. Despite advancements in PH management, progression to RV maladaptation and subsequent failure remain a clinical challenge.
Mark T. Waddingham, Hirotsugu Tsuchimochi, Takashi Sonobe, Vasco Sequeira, Md Junayed Nayeem, Mikiyasu Shirai, James T. Pearson, Takeshi Ogo   +7 more
doaj   +1 more source