Results 91 to 100 of about 39,514 (227)

Hormone replacement therapy [PDF]

, 2012
Martha Hickey, Jane Elliott, Sonia Louise ...
Davison, S., Elliott, C., Hickey, M.
core   +2 more sources

The importance of longitudinal evaluation using DAT‐SPECT in organophosphate‐induced toxic parkinsonism

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
We performed longitudinal evaluation using magnetic resonance imaging (MRI) and dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) in a case of organophosphate‐induced toxic parkinsonism. Fluid‐attenuated inversion recovery (FLAIR) images showed bilateral striatal hyperintensity in the acute phase, followed by reduction of ...
Shuhei Nakao, Yoichiro Kogoh, Hideki Funahashi, Yusei Yanoma, Minako Azuma, Yasushi Ishida, Yoji Hirano   +6 more
wiley   +1 more source

Cognitive function and lifetime features of depression and bipolar disorder in a large population sample: Cross-sectional study of 143,828 UK Biobank participants [PDF]

, 1996
Background: This study investigated differences in cognitive performance between middle-aged adults with and without a lifetime history of mood disorder features, adjusting for a range of potential confounders.
Cullen, B., Deary, I..J., Evans, J.J., Gallacher, J., Mackay, D.F., Martin, D., McIntosh, A., Nicholl, B.I., Pell, J.P., Smith, D.J., Ul-Haq, Z.   +10 more
core   +2 more sources

A Systematic Review and Narrative Synthesis Comparing the Efficacy of Dapoxetine and Clomipramine in the Management of Premature Ejaculation

Trends in Urology &Men's Health, Volume 17, Issue 3, June 2026.
ABSTRACT Dapoxetine (on‐demand SSRI) and clomipramine (daily TCA) are commonly used for premature ejaculation (PE), yet direct comparative evidence remains limited and heterogeneous, particularly because dapoxetine is administered on‐demand while clomipramine requires daily dosing. To systematically review evidence comparing dapoxetine and clomipramine
Khaled Moheyiddin, Ahmed H. Hassan
wiley   +1 more source

Unveiling the efficacy of paroxetine and gabapentin in ulcerative colitis patients in remission with co-existing IBS-like symptoms: a single-blinded randomized clinical trial

Frontiers in Medicine
IntroductionThis clinical trial is designed to explore the efficacy of paroxetine and gabapentin in alleviating functional gastrointestinal symptoms, anxiety, depression, and quality of life in patients with ulcerative colitis during the remission stage ...
Farahnaz Safaei, Shabnam Shahrokh, Nosratollah Naderi, Reyhaneh Rastegar, Alireza Shamsi   +4 more
doaj   +1 more source

Major depression with ischemic heart disease: Effects of paroxetine and nortriptyline on long-term heart rate variability measures [PDF]

, 2002
Background: Studies have linked depression to sudden death and serious cardiovascular events in patients with preexisting cardiac illness. Recent studies have shown decreased vagal function in cardiac patients with depression and depressed patients ...
Jayaraman, A., Pesce, V., Roose, S., Yeragani, V.K.   +3 more
core  

Peeking Inside the Black Box: Visualizing Statistical Learning with Plots of Individual Conditional Expectation

, 2014
This article presents Individual Conditional Expectation (ICE) plots, a tool for visualizing the model estimated by any supervised learning algorithm. Classical partial dependence plots (PDPs) help visualize the average partial relationship between the ...
Bleich, Justin, Goldstein, Alex, Kapelner, Adam, Pitkin, Emil   +3 more
core   +2 more sources

Paroxetine suppresses recombinant human P2X7 responses [PDF]

, 2015
P2X7 receptor (P2X7) activity may link inflammation to depressive disorders. Genetic variants of human P2X7 have been linked with major depression and bipolar disorders, and the P2X7 knockout mouse has been shown to exhibit anti-depressive-like behaviour.
A Bhaskaracharya, A MacKenzie, A McQuillin, AD Michel, AD Michel, AD Michel, AD Michel, AN Shemon, AN Shemon, B Eisensamer, C Coddou, C Hempel, C Virginio, CE Gargett, D Ferrari, DL Donnelly-Roberts, E Toulme, EK Green, F Luo, G Kenis, HJ Bradley, HR Arias, IE Dick, JS Wiley, K Nagata, Kristen K. Skarratt, L Stokes, L Stokes, L Stokes, L Ulmann, Leanne Stokes, M Bourin, M Grigoroiu-Serbanescu, M Maes, M Mahmoodi, M Tsuda, M Viikki, M Zarei, N Barden, P Soronen, Phuong Dao-Ung, R Bartlett, R Dantzer, RT Robinson, S Lucae, SH Jo, Stephen J. Fuller, T Kobayashi, T Kobayashi, W Ma, W Norenberg   +50 more
core   +1 more source

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1385-1396, May 2026.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman, Mathieu Félices, Bhaskar Pandurangavittal, Sanman Ghorpade, Caroline Easterbrook, Marcin Zabielski, Oscar Della Pasqua   +6 more
wiley   +1 more source

Comparative effectiveness of switching paroxetine formulation for treatment of major depressive disorder: an open-label multicenter study

Neuropsychiatric Disease and Treatment, 2018
Tempei Otsubo,1 Yoshinori Watanabe,2,3 Seiji Hongo,3 Mikichika Inoue,4 Kimiko Akimoto,4 Ken Murakami,5 Ryutaro Takahashi,6 Toshiaki Kikuchi7 1Department of Psychiatry, Tokyo Women’s Medical University Medical Center East, Tokyo, Japan; 2Himorogi ...
Otsubo T, Watanabe Y, Hongo S, Inoue M, Akimoto K, Murakami K, Takahashi R, Kikuchi T   +7 more
doaj