Results 21 to 30 of about 39,514 (227)

Paroxetine in the treatment of premature ejaculation: a systematic review and meta-analysis

BMC Urology, 2019
Background Paroxetine is one of the selective serotonin reuptake inhibitors (SSRIs) used in the treatment of premature ejaculation (PE). However, this use is not approved in many countries.
Dong Zhang, Yue Cheng, Kerong Wu, Qi Ma, Junhui Jiang, Zejun Yan   +5 more
doaj   +1 more source

Fluoxetine reduces murine graft-versus-host disease by induction of T cell immunosuppression [PDF]

, 2013
Serotonin reuptake inhibitors (SRIs) are widely used drugs in the treatment of depression and anxiety disorders. Although SRIs are generally regarded as safe drugs with relatively few side effects, literature suggests that high concentrations of SRIs may
Billiau, An D, Deforce, Dieter, Denys, Damiaan, Fevery, Sabine, Gobin, Veerle, Tilleman, Kelly, Van Steendam, Katleen   +6 more
core   +3 more sources

The role of harms and burdens in clinical practice guidelines: Lessons learned from the American Psychological Association's guideline development

Clinical Psychology: Science and Practice, EarlyView., 2020
Abstract Growing evidence supports the efficacy of various psychosocial interventions yet provides very little information about the potential harms and burdens of treatment. Lacking such information makes it difficult to make truly informed decisions about treatment options.
Raquel W. Halfond, Caroline Vaile Wright, Lynn F. Bufka   +2 more
wiley   +1 more source

GRK2 inhibitors, paroxetine and CCG258747, attenuate IgE-mediated anaphylaxis but activate mast cells via MRGPRX2 and MRGPRB2

Frontiers in Immunology, 2022
G protein-coupled receptor (GPCR) kinase 2 (GRK2), which phosphorylates agonist-occupied GPCRs to promote their desensitization, has been investigated as an attractive therapeutic target for cardiovascular and metabolic diseases.
Monica Thapaliya, Aetas Amponnawarat, Aetas Amponnawarat, John J. G. Tesmer, Hydar Ali   +4 more
doaj   +1 more source

Efficacy of new-generation antidepressants assessed with the Montgomery-Asberg depression rating scale, the gold standard clinician rating scale : a meta-analysis of randomised placebo-controlled trials [PDF]

, 2020
It has been claimed that efficacy estimates based on the Hamilton Depression Rating-Scale (HDRS) underestimate antidepressants true treatment effects due to the instrument's poor psychometric properties.
Hengartner, Michael Pascal, Jakobsen, Janus C., Plöderl, Martin, Sørensen, Anders   +3 more
core   +2 more sources

A Randomized Double-blind Placebo-controlled Trial to Assess the Effect of Tamarind seed in Premature Ejaculation

Advanced Biomedical Research, 2018
Background: This randomized clinical trial was aimed to evaluate the effect of oral use of tamarind seed powder as an herbal product in patients affected by premature ejaculation (PE).
Abdulla Homayuonfar, Alireza Aminsharifi, Alireza Salehi, Ali Sahraian, Shadab Dehshari, Mohsen Bahrami   +5 more
doaj   +1 more source

Is there a potential of misuse for venlafaxine and bupropion? [PDF]

, 2018
© 2018 Schifano and Chiappini. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the ...
Anderson, Augustin, Baker, Baribeau, Bolden-Watson, Campagne, Carvalho, Chiappini, Chiappini, Chouinard, Cosci, Cutler, Deluca, Evans, Fava, Fava, Fountain, Francesconi, Groot, Harvey, Harvey, Hill, Hilliard, Holland, Hopper, Hu, Kantor, Kelly, Khurshid, Kim, Koga, Kotzalidis, Langguth, Lewin, Llorca, Maj, McCormick, Muth, Nelson, Orsolini, Parker, Phillips, Quaglio, Redrobe, Reeves, Renoir, Rettew, Rudolph, Sabljić, Schifano, Schifano, Shang, Shenouda, Sir, Stahl, Stahl, Stahl, Stall, Stassinos, Taylor, Vento, Weikop, Welsh, Wilson, Yoon   +64 more
core   +3 more sources

Urticarial lesions associated with the use of paroxetine: a case report

Psychiatry and Clinical Psychopharmacology, 2018
Paroxetine is an antidepressant included in the group of selective serotonin reuptake inhibitors (SSRI) with antidepressant and anxiolytic properties. A rarely seen adverse effect of paroxetine is dermatological reactions.
Rukiye Ay
doaj   +1 more source

Three year naturalistic outcome study of panic disorder patients treated with paroxetine

BMC Psychiatry, 2004
Background This naturalistic open label follow-up study had three objectives: 1) To observe the course of illness in Panic Disorder patients receiving long-term versus intermediate-term paroxetine treatment 2) To compare the relapse rates and side-effect
Lowengrub Katherine, Cohen Ami, Iancu Iulian, Dannon Pinhas N, Grunhaus Leon, Kotler Moshe   +5 more
doaj   +1 more source

Paroxetine Attenuates Cardiac Hypertrophy Via Blocking GRK2 and ADRB1 Interaction in Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background ADRB1 (adrenergic receptor beta 1) responds to neuroendocrine stimulations, which have great implications in hypertension. GRK2 (G protein‐coupled receptor kinase 2) is an essential regulator for many G protein‐coupled receptors and subsequent
Xuejing Sun, Mengli Zhou, Gaiyan Wen, Yun Huang, Junru Wu, Liping Peng, Weihong Jiang, Hong Yuan, Yao Lu, Jingjing Cai   +9 more
doaj   +1 more source