Results 111 to 120 of about 15,382 (226)

Severe cutaneous thrombosis with hemorrhagic necrosis in a patient with paroxysmal nocturnal hemoglobinuria: A case report and review of literature

Dermatologica Sinica, 2017
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, chronic acquired clonal stem cell disorder, typically manifesting hemolysis, pancytopenia and thrombosis in various organs. PNH-associated cutaneous thrombosis is extremely rare.
Fu-Nien Hsieh, Tsai-Yun Chen, Julia Yu-Yun Lee   +2 more
doaj   +1 more source

Paroxysmal Nocturnal Hemoglobinuria with Glucose-6-Phosphate Dehydrogenase Deficiency: A Case Report and Review of the Literature

Case Reports in Oncology, 2019
In this study, we are describing a female patient with paroxysmal nocturnal hemoglobinuria (PNH) and glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Mahmoud S. Eisa, Shehab F. Mohamed, Firyal Ibrahim, Khalid Shariff, Nagham Sadik, Abdulqadir Nashwan, Mohamed A. Yassin   +6 more
doaj   +1 more source

Expert Consensus of Multidisciplinary Diagnosis and Treatment for Paroxysmal Nocturnal Hemoglobinuria(2024)

Xiehe Yixue Zazhi
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal hematopoietic stem cell disease caused by abnormal expression of glycosylphosphatidylinositol (GPI) on the cell membrane due to mutations in the phosphatidylinositol glycan class A(PIGA ...
CHEN Miao, YANG Chen, LIU Ziwei, CAO Wei, ZHANG Bo, LIU Xin, LI Jingnan, LIU Wei, PAN Jie, WANG Jian, ZHENG Yuehong, CHEN Yuexin, LI Fangda, DU Shunda, NING Cong, CHEN Limeng, YUE Cai, NI Jun, PENG Min, GUO Xiaoxiao, WANG Tao, LI Hongjun, LI Rongrong, WU Tong, HAN Bing, ZHANG Shuyang, Multidiscipline Collaboration Group on Rare Disease at Peking Union Medical College Hospital   +26 more
doaj   +1 more source

Preoperative administration of eculizumab to prevent surgery‐triggered hemolysis during cesarean section with paroxysmal nocturnal hemoglobinuria

Clinical Case Reports, 2018
Key Clinical message Eculizumab in pregnancy has been reported to be effective in improving outcomes in patients with paroxysmal nocturnal hemoglobinuria. However, a cesarean section may result in surgery‐triggered hemolysis.
Dongping Li, Liangcheng Wang, Isao Horiuchi, Shun‐ichi Kimura, Kenro Chikazawa, Azusa Kimura, Shigetane Sasaki, Tomoyuki Kuwata, Kenjiro Takagi   +8 more
doaj   +1 more source

Current Insights into Paroxysmal Nocturnal Hemoglobinuria

Siriraj Medical Journal, 2020
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Wanchai Wanachiwanawin
doaj  

Successful haploidentical hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria with severe pancytopenia developed after long‐term aplastic anemia treatment

Clinical Case Reports
Key Clinical Message Haploidentical hematopoietic stem cell transplantation (HSCT) with posttransplant cyclophosphamide is an alternative treatment for aplastic anemia–paroxysmal nocturnal hemoglobinuria (PNH) syndrome with poor prognostic factors ...
Kazuki Sakurai, Kei Saito, Shunsuke Hatta, Yuna Katsuoka, Kuniaki Meguro, Hisayuki Yokoyama, Toru Izumi   +6 more
doaj   +1 more source

SYNOPSIS IS A RARE CASE OF ORPHAN CO-MORBIDITY. EXPERIENCE IN TREATING A PATIENT WITH APLASTIC AND CLONOXYSMAL NOCTURNAL HEMOGLOBINURIA

Медицина в Кузбассе
Paroxysmal nocturnal hemoglobinuria (APG) is a rare clonal disease, an acquired form of hemolytic anemia from the group of rare (orphan) diseases. A characteristic clinical manifestation with a significant APG clone (usually more than 10 % of the total ...
Дмитрий Михайлович Неверов, Марина Владимировна Косинова, Светлана Ивановна Елгина, Елена Владимировна Рудаева, Кира Борисовна Мозес, Наталья Степановна Черных   +5 more
doaj  

Anticomplement therapy

Biologics: Targets & Therapy, 2009
Prathit A Kulkarni1, Vahid Afshar-Kharghan21Baylor College of Medicine, Houston, Texas, USA; 2The University of Texas, M.D. Anderson Cancer Center, Houston, Texas, USAAbstract: The complement system is an important part of innate immunity; however, as ...
Prathit A Kulkarni, Vahid Afshar-Kharghan   +1 more
doaj  

A Case Presenting with Acute Kidney Injury and Paroxysmal Nocturnal Hemoglobinuria

Turkish Journal of Nephrology, 2019
There may be different clinical presentations of kidney involvement in the course of paroxysmal nocturnal hemoglobinuria, within a spectrum of acute kidney injury, generally due to hemolysis, to chronic kidney disease.
Ezgi ÇOŞKUN YENİGÜN, Didem TURGUT, Simge BARDAK, Serhan PİŞKİNPAŞA, Nihal ÖZKAYAR, Eyüp KOÇ, Fatih DEDE   +6 more
doaj  

Paroxysmal nocturnal hemoglobinuria pnh

Hematology, Transfusion and Cell Therapy, 2020
Hanan Hamed
doaj   +1 more source