Results 91 to 100 of about 82,322 (154)

Current Insights into Paroxysmal Nocturnal Hemoglobinuria

Siriraj Medical Journal, 2020
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Wanchai Wanachiwanawin
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Dual-Beam optical Manipulation of Red blood cells for the investigation of paroxysmal nocturnal hemoglobinuria

, 2022
© 2021 The Author(s).Paroxysmal nocturnal hemoglobinuria was studied using dual-beam optical tweezers. Force measurements show a moderate change between disease and healthy states.
Soysal, Kaan Batu, Yenerel, Mustafa, Ozbalak, Mustafa Murat, Unlu, Burcin, Mastanzade, Metban, Parlatan, Seyma, Parlatan, Ugur   +6 more
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Model-Informed Precision Dosing of Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria.

Contains fulltext : 322381.pdf (Publisher’s version ) (Open Access)BACKGROUND AND OBJECTIVE: Eculizumab is an expensive therapeutic monoclonal antibody inhibiting complement C5 and approved for various indications, including the rare ...
Heuvel, L.P.W.J. van den, Kar, N.C.A.J. van de, Heine, R. ter, Avest, M. ter, Langemeijer, S.M.C., Baas, L.M.   +5 more
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Successful haploidentical hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria with severe pancytopenia developed after long‐term aplastic anemia treatment

Clinical Case Reports
Key Clinical Message Haploidentical hematopoietic stem cell transplantation (HSCT) with posttransplant cyclophosphamide is an alternative treatment for aplastic anemia–paroxysmal nocturnal hemoglobinuria (PNH) syndrome with poor prognostic factors ...
Kazuki Sakurai, Kei Saito, Shunsuke Hatta, Yuna Katsuoka, Kuniaki Meguro, Hisayuki Yokoyama, Toru Izumi   +6 more
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Paroxysmal nocturnal hemoglobinuria: Diagnosis and management protocol

, 2014
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired, rare clonal blood disorder, characterized by chronic intravascular hemolysis, bone marrow failure, renal failure and pulmonary hypertension, and a heightened risk of thrombotic complications.
Mahmoud Almarashly, Mohammad Aslam, Salam Al Kindi, Wafaa Bassuni, Hazzaa Alzahrani, Faisal Alsayegh, Fahed Almhareb, Ayman Hejazi, Rania Seliem, Saud Abuharbesh, Abdul Ghani Al Bakistani, Mohammad Qari, TareK Owaidah, Abdul Kareem Almomen, Ahmad Alsaeed, Asma Al Olama, Christian Awarji   +16 more
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PAROXYSMAL NOCTURNAL HEMOGLOBINURIA IN CHILDHOOD: AN UNCOMMON PRESENTATION [PDF]

, 2006
An eight year old boy presented with severe anemia and bleeding spots. Complete blood count showed pancytopenia. There was mild reticulocytosis. Bone marrow was hypocellular with normoblastic erythroid hyperplasia.
V. Tilak, S. V. K. Ramakrishna, B. D. Bhatia, V. Gupta   +3 more
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The immune response dis-regulation and the pathogenesis of hematopoietic disorders [PDF]

, 2008
Sica, Michela
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Baseline characteristics and disease burden in patients in the International Paroxysmal Nocturnal Hemoglobinuria Registry

Paroxysmal nocturnal hemoglobinuria is a rare, acquired disease associated with hemolytic anemia, bone marrow failure, thrombosis, and, frequently, poor quality of life.
Khursigara, Gus, Szer, Jeffrey, Brodsky, Robert A., Kanakura, Yuzuru, Urbano Ispizua, Álvaro, Schrezenmeier, Hubert, Hillmen, Peter, Muus, Petra, Maciejewski, Jaroslaw P., Socié, Gérard, Bessler, Monica, Bedrosian, Camille L., Rosse, Wendell   +12 more
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Paroxysmal nocturnal hemoglobinuria presenting as acute renal injury [PDF]

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired chronic hemolytic anemia characterized by persistent intravascular hemolysiswith occasional or frequent recurrent exacerbations.
Biswal, Anshuman, Puri, Rohit, Jatteppanavar, Basavaraj, Koley, Himadri, Ahlawat, Parul, Dhoot, Dipesh K., Karunanidhi, Devada S., Cheluvaiah, Chandrashekar, Saini, Sandeep   +8 more
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SYNOPSIS IS A RARE CASE OF ORPHAN CO-MORBIDITY. EXPERIENCE IN TREATING A PATIENT WITH APLASTIC AND CLONOXYSMAL NOCTURNAL HEMOGLOBINURIA

Медицина в Кузбассе
Paroxysmal nocturnal hemoglobinuria (APG) is a rare clonal disease, an acquired form of hemolytic anemia from the group of rare (orphan) diseases. A characteristic clinical manifestation with a significant APG clone (usually more than 10 % of the total ...
Дмитрий Михайлович Неверов, Марина Владимировна Косинова, Светлана Ивановна Елгина, Елена Владимировна Рудаева, Кира Борисовна Мозес, Наталья Степановна Черных   +5 more
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