Results 61 to 70 of about 23,848 (306)

Seizures During Exercise

Pediatric Neurology Briefs, 1988
Three children with epileptic seizures occurring during exercise are reported from the Section of Electroencephalography and Pediatric Neurology, Mayo Clinic, Rochester, MN.
J Gordon Millichap
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Mechanisms of paroxysmal atrial fibrillation in patients with sick sinus syndrome

Российский кардиологический журнал, 2004
Atrial ectopic activity and atrial conduction in patients with paroxysmal atrial fibrillation (AF) and sick sinus syndrome (SSS) were investigated.
S. Yu. Ivanov, N. N. Burova, B. B. Bondarenko   +2 more
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

RADIOFREQUENCY ABLATION IN ATRIAL TACHYCARDIA PAROXYSM ON EXAMPLE OF CLINICAL CASE

Journal of V. N. Karazin Kharkiv National University: Series Medicine, 2018
The disappearance of atrial tachycardia paroxysms after radiofrequency catheter ablation (RFA) of ectopic focus in a left atrium is presented on example of clinical case. Atrial tachycardia paroxysms disappeared after ablation completely.
Brynza M. S., Zaporiz’ka V. V., Vasylenko O. A., Volkov D. E.   +3 more
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

CLINICAL EFFICACY AND SAFETY OF SEIZING PAROXYSMS OF ATRIAL FIBRILLATION WITH PROPAPHENON

Российский кардиологический журнал, 2003
The study was made to evaluate clinical efficacy, safety and electrophysiological effects of Propaphenon in seizing paroxysms of atrial fibrillation (AF)45 patients have been evaluated, with AF paroxysms lasting up to 48 hours.
A. Zakhar, I. V. Antonchenkov, E. V. Borisova, S. V. Popov, I. O. Kurlov   +4 more
doaj  

Clinical insights on Tolosa Hunt syndrome: a multidisciplinary approach on neurological-related symptomatology in maxillofacial region [PDF]

, 2018
Background Tolosa–Hunt syndrome (THS) related neurological symptoms are described in literature as “unilateral”, “recurrent”, “episodic”, “intense”, “severe”, “lancinating” or “stabbing” pain on the upper face and forehead and may be misdiagnosed ...
Ahmed Siddiqui, Ammar, Ali Khan, Zafar, Aziz Alanizy, Hamoud, Bollero, Patrizio, Cicconetti, Andrea, Falisi, Giovanni, Inchingolo, Francesco, Orefici, Alessandro, Syed, Jamaluddin   +8 more
core   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source