Results 51 to 60 of about 531,329 (309)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
ZATRUDNIENIE W NIEPEŁNYM WYMIARZE CZASU PRACY
Zeszyty Prawnicze, 2017 Time-part Employment – Chances and Threats Summary Over the last twenty years, an increasing share of employment across the EU countries has been made up of part time jobs.
Barbara Surdykowska
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Labour market flexibility as a factor in economic recovery after the COVID-19 pandemic
Journal of New EconomyThe COVID-19 pandemic has largely undermined most economies in the world. To a significant extent the reasons behind this economic nosedive are rooted in the sphere of labour market.
Maria Ye. Konovalova +2 more
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
NON-STANDARD FORMS OF EMPLOYMENT IN BUSINESS ORGANIZATIONS
Модернизация, инновация, развитие, 2015 The article discusses the emergence and development of non-standard forms of employment and flexible working. The causes of their use reflects the results of research conducted in the workplace.
A. E. Chekanov
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Flexible approach to the four-day workweek: from theory to implementation
Вестник университетаThe purpose of this study is to identify key trends in employee expectations and readiness to transition to reduced work hours. Based on the results of exploratory research conducted by the author, this article ana lyses the opportunities and desires of ...
N. V. Chaplashkin
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
WP 34 - Female part-time employment in the Netherlands [PDF]
Part-time workers have achieved legal equality throughout the European Union-15 (EU-15), although the situation concerning real equality is rather different: it exists in some Member States but not in others.
Sirvent Garcia del Valle, E.
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