Results 201 to 210 of about 205,233 (331)

Evaluation of the Sedative Properties of PK 8165 (Pipequaline). a Benzodiazepine Partial Agonist, in Normal Subjects

, 1986
R. von Frenckell, Marc Ansseau, DOMINIQUE BONNET   +2 more
openalex   +2 more sources

Treating symptomatic hyperprolactinemia in women with schizophrenia: presentation of the ongoing DAAMSEL clinical trial (Dopamine partial Agonist, Aripiprazole, for the Management of Symptomatic ELevated prolactin) [PDF]

, 2013
Deanna L. Kelly, Heidi J. Wehring, Amber Earl, Kelli M. Sullivan, Faith Dickerson, Stephanie Feldman, Robert P. McMahon, Robert W. Buchanan, Dale Warfel, William R. Keller, Bernard A. Fischer, Joo-Cheol Shim   +11 more
openalex   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Emerging Clinical Role of Tavapadon, a Novel Dopamine Partial Agonist, in the Treatment of Parkinson's Disease. [PDF]

Diseases
Kaye AD, Ford BM, Abbott BM, Broocks KM, Novacic S, Shekoohi S.   +5 more
europepmc   +1 more source

Partial Agonist Activity of Neonicotinoids on Rat Nicotinic Receptors: Consequences over Epinephrine Secretion and In Vivo Blood Pressure. [PDF]

Int J Mol Sci, 2021
Park J, Taly A, Bourreau J, De Nardi F, Legendre C, Henrion D, Guérineau NC, Legros C, Mattei C, Tricoire-Leignel H.   +9 more
europepmc   +1 more source

Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N‐methyl‐D‐aspartate receptor.

, 1990
Graeme Henderson, John Johnson, Philippe Ascher   +2 more
openalex   +2 more sources

An assessment of the partial agonist activity of Ro 31‐1118, flusoxolol and pindolol in man. [PDF]

, 1987
P. M. McCaffrey, JG Riddell, RG Shanks
openalex   +1 more source

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source

Novel Benzoisoxazole as Partial Agonist of the 5-HT4 Receptor

, 2012
Gérard Rossé
openalex   +1 more source

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen, Rui Li, Yong She, Xuefei Liu, Yuanyang Huang, Yongling Ji, Keying Chen, Zhengbo Song, Runzhe Chen, Xuan Li, Qi Zhao, Qixun Chen, Ming Chen   +12 more
wiley   +1 more source