Results 311 to 320 of about 205,233 (331)

GABAA Receptor Agonists, Partial Agonists, and Antagonists

1997
The neutral amino acid, γ-aminobutyric acid (GABA), is an inhibitory transmitter in the central nervous system (CNS). Furthermore, GABA is involved as a neurotransmitter and/or a paracrine effector in the regulation of a variety of physiological mechanisms in the periphery.
Frølund, Bente, Krogsgaard-Larsen, Povl, Ebert, Bjarke   +2 more
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Dopamine Partial Agonists

CNS Drugs, 2004
This review examines the development of dopamine partial agonists as a new class of antipsychotic agents. Partial agonists have a lower intrinsic activity at receptors than full agonists, allowing them to act either as a functional agonist or a functional antagonist, depending on the surrounding levels of naturally occurring neurotransmitter (full ...
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Oxyfedrine — A partial agonist at β-adrenoceptors

European Journal of Pharmacology, 1972
Abstract Oxyfedrine, 0.5 μg/ml, caused typical but long lasting sympathomimetic effects on guinea-pig atria and trachealis, rabbit atria and duodenum and rat uterus and perfused heart. These effects were antagonised by propranolol. The heart rate and blood pressure of the anaesthetised rat also showed sympathomimetic responses.
P R, Beckett, R W, Foster
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ChemInform Abstract: Mixed Opioidic Agonists/Antagonists and Partial Agonists

ChemInform, 2002
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Thomas Christoph, Helmut Buschmann
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Do Dopamine Partial Agonists Have Partial Efficacy as Antipsychotics?

CNS Spectrums, 2008
CNS Spectr 13:4 April 2008 279 NEW TREND IN PSYCHOPHARMACOLOGY Dopamine (D)2 partial agonists (DPAs) activate D2 receptors in a manner that is less than the full agonist dopamine yet more than full antagonists (eg, most known antipsychotics). Various DPAs span the spectrum between full agonist at one end and antagonists at the other, with the ...
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Antiestrogens and Partial Agonists

1999
For more than a decade, the antiestrogen tamoxifen dominated the field of estrogen antagonists despite its inherent estrogenicity. For a long time, efforts to replace tamoxifen or improve its pharmacological profile by structural modifications have failed.
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Benzodiazepine partial agonists

Journal of Psychopharmacology, 1993
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Partial Agonist

2010
R. Hamish McAllister-Williams, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Linda P. Spear, Tim C. Kirkham, Thomas Steckler, Delphine Capdevielle, Jean-Philippe Boulenger, Delphine Capdevielle, Jean-Philippe Boulenger, Delphine Capdevielle, Jean-Philippe Boulenger, Cyril Höschl, Martine Cador, Ben J. Harrison, Christos Pantelis, Anthony Riley, Steve Kohut, Alex Hofer, Ben J. Harrison, Christos Pantelis, Seithikurippu R. Pandi-Perumal, D. Warren Spence, Shelby Freedman Harris, Michael J. Thorpy, Milton Kramer, Ian Stolerman, Holden D. Brown, Michael Ragozzino, Klaus A. Miczek, Anne Jackson, Sven Ove Ögren, Oliver Stiedl, Paul R. Pentel, Mark LeSage, Victoria L. Harvey, Tony Dickenson, Christine A. Franco, Marc N. Potenza, Gail Winger, Mei-Chuan Ko, James H. Woods, Matthew I. Palmatier, Rick A. Bevins, Stephan G. Anagnostaras, Jennifer R. Sage, Stephanie A. Carmack, Jos Prickaerts, Jos Prickaerts, Jos Prickaerts, Warren H. Meck, Catalin V. Buhushi, Christoph U. Correll, Ian Stolerman, Mohammed Shoaib, Trevor Robbins, Daniel Hoyer, Thomas Steckler, Linda P. Spear, Luzio Tremolizzo, Gessica Sala, Carlo Ferrarese, Seiya Miyamoto, Thomas Steckler, David S. Tait, Verity J. Brown, Richard A. Depue, Tara L. White, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Craig A. Erickson, David J. Posey, Kelly Blankenship, Kimberly A. Stigler, Christopher J. McDougle, Ian Stolerman, Jean-Michel Scherrmann, S. Stevens Negus, Dana E. Selley, Laura J. Sim-Selley, Christoph Hiemke, Sophie Tambour, John C. Crabbe, Pierre Baumann, Kim Wolff, Christof Baltes, Thomas Mueggler, Markus Rudin, Alan J. Budney, Robert L. Balster, Sharon Walsh, Robert L. Balster, Sharon Walsh, Robert L. Balster, Sharon Walsh, Andrea Bari, Johannes Mosbacher, Paul Willner, Klaus A. Miczek, Trevor Robbins, Wolfgang Fleischhacker, Etienne Sibille, Nicole Edgar, Sabine M. Hölter, John F. Cryan, Michel Le Moal, Marco Leyton, Sara Tomlinson, Glen Baker, Bernard Le Foll, Naheed (Max) Mirza, Tomasz Schneider, Jos Prickaerts, Jos Prickaerts, Robert L. Balster, Sharon Walsh, Yogita Chudasama, Thomas Steckler, Thomas Steckler, Daniel Hoyer, Stan Floresco, Christine A. Franco, Marc Potenza, Fabrizio Benedetti, Peter Riederer, Siegfried Hoyer, Luzio Tremolizzo, Gessica Sala, Carlo Ferrarese, Luzio Tremolizzo, Gessica Sala, Carlo Ferrarese, Lucio Tremolizzo, Gessica Sala, Carlo Ferrarese, Arthur Christopoulos, Gregory D. Stewart, Patrick M. Sexton, Christoph Hiemke, Malcolm Lader, Stefan Leucht, Mark Slifstein, Linda P. Spear, Samuel G. Siris, Susan Jones, Peter Verheart, Per Svenningsson, Per Andrén, Seithikurippu R. Pandi-Perumal, Milton Kramer, Michael J. Thorpy, Shelby Freedman Harris, D. Warren Spence, John Atack, Hilde Lavreysen, Stephen C. Fowler, Harriet de Wit, Britta Hahn, Stephen C. Fowler, Helen Cassaday, Paul Willner, Darren R. Christensen, Warren K. Bickel, Michael Minzenberg, David Baldwin, C. Neill Epperson, C. Neill Epperson, Lawrence Scahill, I. T. Uzbay, Lisiane Bizarro, Bart Ellenbroek, Linda P. Spear, Patrick D. McGorry, Alison R. Yung, Mark A. Geyer, Johannes Mosbacher, Malcolm Lader, Angela Roberts, Celia Morgan, Valerie Curran, Christine A. Franco, Marc Potenza, Celia Morgan, Valerie Curran, Thomas Steckler, Harriet de Wit, Jill B. Becker, Mary Cain, Michael T. Bardo, Thomas Steckler, Trevor Robbins, Theodora Duka, Sam Hutton, C. Neill Epperson, Celia Morgan, Valerie Curran   +199 more
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Partial agonists for adenosine receptors

1996
Publisher Summary This chapter discusses the partial agonists for adenosine receptors. Adenosine is generally considered as a “local hormone” with profound physiological activity. It is thought to mediate a large variety of effects, as diverse as vasodilation in the cardiovascular system, inhibition of lipolysis in fat cells, and depression of ...
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PARTIAL BENZODIAZEPINE AGONISTS

Clinical Neuropharmacology, 1984
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