Results 71 to 80 of about 1,441,473 (315)

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

λ-Symmetry and μ-Symmetry Reductions and Invariant Solutions of Four Nonlinear Differential Equations

open access: yesMathematics, 2020
On one hand, we construct λ-symmetries and their corresponding integrating factors and invariant solutions for two kinds of ordinary differential equations.
Yu-Shan Bai, Jian-Ting Pei, Wen-Xiu Ma
doaj   +1 more source

On stochastic differential equations and a generalised Burgers equation [PDF]

open access: yes, 2012
In this paper, we discuss a link of Itˆo’s stochastic differential equa- tions to nonlinear partial differential equations of Burgers type. Un- der certain conditions, we derive a generalised Burgers equation from a stochastic differential equation.
Wu, JiangLun, Yang, Wei
core  

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

On singular solutions of a multidimensional differential equation of Clairaut-type with power and exponential functions

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2019
In the theory of ordinary differential equations, the Clairaut equation is well known. This equation is a non-linear differential equation unresolved with respect to the derivative.
Liliya Leonidovna Ryskina
doaj   +1 more source

Finite element analysis for a coupled bulk-surface partial differential equation

open access: yes, 2013
In this paper, we define a new finite element method for numerically approximating the solution of a partial differential equation in a bulk region coupled with a surface partial differential equation posed on the boundary of the bulk domain.
C. M. Elliott, T. Ranner
semanticscholar   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

A Procedure to Construct Exact Solutions of Nonlinear Fractional Differential Equations

open access: yesThe Scientific World Journal, 2014
We use the fractional transformation to convert the nonlinear partial fractional differential equations with the nonlinear ordinary differential equations.
Özkan Güner, Adem C. Cevikel
doaj   +1 more source

Explicit Exact Solutions of the (2+1)-Dimensional Integro-Differential Jaulent–Miodek Evolution Equation Using the Reliable Methods

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2020
In this article, we utilize the G′/G2-expansion method and the Jacobi elliptic equation method to analytically solve the (2 + 1)-dimensional integro-differential Jaulent–Miodek equation for exact solutions.
Supaporn Kaewta   +2 more
doaj   +1 more source

Hybrid deterministic stochastic systems with microscopic look-ahead dynamics [PDF]

open access: yes, 2010
We study the impact of stochastic mechanisms on a coupled hybrid system consisting of a general advection-diffusion-reaction partial differential equation and a spatially distributed stochastic lattice noise model.
Katsoulakis, M. A.   +2 more
core  

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