Results 31 to 40 of about 36,653 (266)

Sex Hormone-Related Functions in Regenerating Male Rat Liver [PDF]

, 1986
Sex hormone receptors were quantitated in normal male rat liver and in regenerating liver at several different times after partial (70%) hepatectomy. Both estrogen and androgen receptor content were altered dramatically by partial hepatectomy.
Aquilino, AM, DiLeo, A, Eagon, PK, Francavilla, A, Ingrosso, M, Panella, C, Polimeno, L, Starzl, TE, Van Thiel, DH   +8 more
core   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source

Accumulation and release of triglycerides by rat liver following partial hepatectomy

Journal of Lipid Research, 1970
Regenerating liver accumulates lipid for about 20 hr following partial hepatectomy. During this time incorporation of intravenously administered palmitate-9,10-3H into βlipoprotein increased.
THOMAS J. DELAHUNTY, DAVID RUBINSTEIN
doaj   +1 more source

Preoperative Beta-Hydroxy-Beta-Methyl-Butyrate Supplementation Reduces Mitochondrial Dynamics Proteins and Preserves Hepatic Mitochondrial Function After Partial Hepatectomy in Mice. [PDF]

Acta Physiol (Oxf)
ABSTRACT Aim The liver exhibits a remarkable regenerative capacity, enabling this organ to maintain homeostasis even after significant injury. However, hepatic regeneration requires sufficient energy to sustain cellular hypertrophy and proliferation, thus ensuring efficient tissue repair.
Vieira-da-Silva AL, Esteca MV, Silva FA, Divino IA, Carneiro FS, Ropelle ER, Torsoni AS, Baptista IL.   +7 more
europepmc   +2 more sources

Effect of nebivolol on liver regeneration in an experimental 70% partial hepatectomy model

Asian Journal of Surgery, 2017
Background: Factors affecting liver regeneration are still relevant. The purpose of this study is to investigate the effect of nebivolol treatment on liver regeneration in rats in which 70% partial hepatectomy was performed.
Fatih Sumer, Muhammet Kadri Colakoglu, Yilmaz Ozdemir, Oguzhan Ozsay, Ozer İlter, Erdal Birol Bostanci, Musa Akoglu   +6 more
doaj   +1 more source

LAPAROSCOPIC LIVER RESECTION IN THE GOAT [PDF]

Basrah Journal of Veterinary Research, 2015
The aim of this study is to evaluate application of laparoscopy in veterinary surgery and assess the feasibility safety of laparoscopic hepatectomy using thermal energy to control the bleeding after the partial hepatoctomy in the goats.
Jinan A. bannai, Abdulbari A. Al faris, Rana K. abdulsamd   +2 more
doaj   +1 more source

RAGE limits regeneration after massive liver injury by coordinated suppression TNF-α and NF-κB [PDF]

, 2005
The exquisite ability of the liver to regenerate is finite. Identification of mechanisms that limit regeneration after massive injury holds the key to expanding the limits of liver transplantation and salvaging livers and hosts overwhelmed by carcinoma ...
Cataldegirmen, Guellue, Zeng, Shan, Feirt, Nikki, Ippagunta, Nikalesh, Dun, Hao, Qu, Wu, Lu, Yan, Rong, Ling Ling, Hofmann, Marion A, Kislinger, Thomas, Pachydaki, Sophia I, Jenkins, Daniel G, Weinberg, Alan, Lefkowitch, Jay, Rogiers, Xavier, Yan, Shi Fang, Schmidt, Ann Marie, Emond, Jean C   +17 more
core   +1 more source

Transcriptome sequencing and metabolome analysis reveal the metabolic reprogramming of partial hepatectomy and extended hepatectomy

BMC Genomics, 2023
Surgical resection remains a critical treatment option for many patients with primary and secondary hepatic neoplasms. Extended hepatectomy (eHx) may be required for some patients with large tumors, which may cause liver failure and death.
Zeyuan Li, Bo Peng, Shilian Chen, Jiaping Li, Kai Hu, Lijuan Liao, Qiuli Xie, Mei Yao, Lixing Liang, Stephen Tomlinson, Guandou Yuan, Songqing He   +11 more
doaj   +1 more source

Regenerating Rat Liver: Correlations Between Estrogen Receptor Localization and Deoxyribonucleic Acid Synthesis [PDF]

, 1984
Estrogen receptor activity was quantitated in the cytosol and nucleus of normal rat liver and in regenerating rat liver at several time intervals after 75% hepatectomy. Cytosolic estradiol binding in regenerating liver decreases at 12, 24, and 48 h after
Di Leo, A, Eagon, PK, Francavilla, A, Ove, P, Starzl, TE, Van Thiel, DH, Wu, SQ   +6 more
core   +1 more source

Cerium oxide nanoparticles improve liver regeneration after acetaminophen-induced liver injury and partial hepatectomy in rats

Journal of Nanobiotechnology, 2019
Background and aims Cerium oxide nanoparticles are effective scavengers of reactive oxygen species and have been proposed as a treatment for oxidative stress-related diseases.
Bernat Córdoba-Jover, Altamira Arce-Cerezo, Jordi Ribera, Montse Pauta, Denise Oró, Gregori Casals, Guillermo Fernández-Varo, Eudald Casals, Victor Puntes, Wladimiro Jiménez, Manuel Morales-Ruiz   +10 more
doaj   +1 more source