Results 81 to 90 of about 4,748,115 (286)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Conrad’s Partial Order on P.Q.-Baer *-Rings
Discussiones Mathematicae - General Algebra and Applications, 2018 We prove that a p.q.-Baer *-ring forms a pseudo lattice with Conrad’s partial order and also characterize p.q.-Baer *-rings which are lattices. The initial segments of a p.q.-Baer *-ring with the Conrad’s partial order are shown to be an orthomodular ...
Khairnar Anil, Waphare B.N.
doaj +1 more source
Nonlinear differential equation with first order partial derivatives
Вестник КазНУ. Серия математика, механика, информатика, 2018 The asymptotic behavior of solutions of a nonlinear differential equation with first-order partial derivatives solved with respect to one of the derivatives is investigated.
T. М. Aldibekov, M. M. Aldazharova
doaj +1 more source
Partial Symbol Ordering Distance
, 2009 Nowadays sequences of symbols are becoming more important, as they are the standard format for representing information in a large variety of domains such as ontologies, sequential patterns or non numerical attributes in databases. Therefore, the development of new distances for this kind of data is a crucial need.
Herranz Sotoca, Javier +1 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
On a linear system of differential equations
Вестник КазНУ. Серия математика, механика, информатика, 2019 The linear systems of partial differential equations of the first order with the identical main parts is considered. Аpplying the well-known relation between a normal system of ordinary differential equations and a linear system of partial differential
T. М. Aldibekov, M. M. Aldazharova
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The Fujiki class and positive degree maps
Complex Manifolds, 2015 We show that a map between complex-analytic manifolds, at least one ofwhich is in the Fujiki class, is a biholomorphism under a natural condition on the second cohomologies.
Bharali Gautam +2 more
doaj +1 more source
Shape maps for second order partial differential equations
, 2015 We analyse the singularity formation of congruences of solutions of systems of second order PDEs via the construction of \emph{shape maps}. The trace of such maps represents a congruence volume whose collapse we study through an appropriate evolution ...
Prince, G. E. +2 more
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