Results 51 to 60 of about 30,865 (296)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A novel concept of solar photovoltaic partial shading and thermal hybrid system for performance improvement

EAI Endorsed Transactions on Energy Web
Large values from external causes, such as partial shade, can greatly influence output power of PV. The applications of partial shading are frequently utilized in simulation software. However, in this research work, partial shading and the integration of
Usha S, Geetha P, Geetha A, Balamurugan K S, Selciya Selvan   +4 more
doaj   +1 more source

Efficient Photovoltaic System Maximum Power Point Tracking Using a New Technique

Energies, 2016
Partial shading is an unavoidable condition which significantly reduces the efficiency and stability of a photovoltaic (PV) system. When partial shading occurs the system has multiple-peak output power characteristics.
Mehdi Seyedmahmoudian, Ben Horan, Rasoul Rahmani, Aman Maung Than Oo, Alex Stojcevski   +4 more
doaj   +1 more source

An Enhanced Adaptive Perturb and Observe Technique for Efficient Maximum Power Point Tracking Under Partial Shading Conditions

Applied Sciences, 2020
In this paper, we propose enhanced adaptive step size Perturb and Observe (P&O) maximum power point tracking (MPPT) with properly organized comparison sequences which lead to achieving the actual maximum power point (MPP) effectively in the presence of ...
Altwallbah Neda Mahmod Mohammad, Mohd Amran Mohd Radzi, Norhafiz Azis, Suhaidi Shafie, Muhammad Ammirrul Atiqi Mohd Zainuri   +4 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Maximum Power Enhancement of Partially Shaded Photovoltaic Array by Advanced Total Cross-Tied Based Configuration

Journal of Engineering Technology and Applied Physics
Partial shading in solar photovoltaic arrays reduce the maximum power produced. Partial shading conditions in PV arrays can be caused by water, dust, tree shadows, bird-drops, nearby building, etc.
Kaung Khant Win, Yin Yin Mya
doaj   +1 more source

Enhancement of Rooftop Photovoltaic Array Characteristic Interconnected by Grid under Partial Shading Condition Using Cascaded DC/DC Converter [PDF]

Iranica Journal of Energy and Environment, 2018
The photovoltaic (PV) Power generation is the best source of renewable energy due to advantages such as free fuel cost, cleanness, little maintenance, and causing no noise due to absence of moving parts.
A. M. Mahmoud, S. M. Saafan, A. M. Attalla, H. Elgohary   +3 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Método de estimativa da influência do sombreamento parcial na geração energética de sistemas solares fotovoltaicos integrados em edificações [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-graduação em Engenharia Civil, Florianópolis, 2014.Sistemas fotovoltaicos integrados a edificações inseridas em meio urbano tendem a receber sombreamentos ...
Zomer, Clarissa Debiazi
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