Results 61 to 70 of about 30,865 (296)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Experimental Investigation of the Effects of Partial Shading on Photovoltaic Cells’ Electrical Parameters

International Journal of Photoenergy, 2015
The short-circuit current (Isc), the open-circuit voltage (Voc), and the maximum power point (VMPP, IMPP) of monocrystalline and multicrystalline silicon solar cells under three kinds of partial shading patterns have been investigated experimentally. The
W. B. Xiao, F. Y. Hu, H. M. Zhang, H. M. Wu   +3 more
doaj   +1 more source

Numerical modeling, simulation and evaluation of conventional and hybrid photovoltaic modules interconnection configurations under partial shading conditions

EPJ Photovoltaics, 2022
Partial shading on solar photovoltaic (PV) arrays is a prevalent problem in photovoltaic systems that impair the performance of PV modules and is responsible for reduced power output as compared to that in standard irradiance conditions thereby resulting
Saeed Faisal, Tauqeer Haider Ali, Gelani Hasan Erteza, Yousuf Muhammad Hassan, Idrees Asad   +4 more
doaj   +1 more source

Three Shades of Partial Protection in Elastic Optical Networks

CoRR, 2021
Partial protection strategies based on the observation that in failure events, a service can tolerate a certain amount of degradation and therefore by reducing the protection traffic in the network, better spectrum utilization could be attained. Such concept has been widely studied in the traditional WDM context and yet has been somehow faded due to ...
openaire   +2 more sources

PSO Control under Partial Shading Conditions

Algerian Journal of Renewable Energy and Sustainable Development, 2020
The change observed in new habits and traditions of human beings has significantly influenced the way of their current life especially in their needs for electrical energy.This has consequently increased the demand for energy, which has forced the researchers and the industrials to focus their efforts in the development of electricity production ...
Amira Lakhdara, Tahar Bahi, Abdelkarim Moussaoui   +2 more
openaire   +2 more sources

Probabilistic Modeling of Partial Shading of Photovoltaic Arrays [PDF]

International Journal of Photoenergy, 2015
The probabilistic modeling technique is used in this paper to ascertain the performance of energy conversion of a photovoltaic (PV) array under the influence of partial shading. Three cases of increasing complexity are studied in this paper. The first case is to find the probability density function (pdf) of the maximum power output (MPO) of a single ...
Yaw-Juen Wang, Ruey-Long Sheu
openaire   +2 more sources

The Effect of Partial Shadings on the Output Power of the Photovoltaic Modules Connected with Different Current and Voltage Characteristics

Jurnal Rekayasa Elektrika
A mismatch in the output power of photovoltaic (PV) modules in a PV array can occur due to partial shading or a module replacement. Substitution of a module in a PV array with a new one might lead to different current and voltage characteristics between ...
Ira Devi Sara, Aidil Aqsa SH, Tarmizi Tarmizi   +2 more
doaj   +1 more source

Performance improvement of PV systems during dynamic partial shading conditions using optimization algorithms [PDF]

PV power plants encounter varying levels of irradiance, temperature fluctuations, and partial shading because of the differences in sunlight conditions.
Keerthi Sonam Soma, R., Balamurugan, N., Karuppiah   +2 more
core   +1 more source