Results 121 to 130 of about 2,300,073 (304)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Sum-rate maximization for multiple users in partial frequency reuse cellular networks
, 2010 We apply constrained optimization techniques to optimally allocate the bandwidth and power to the users in a cellular network. We investigate partial frequency reuse with multiple users in the full and partial frequency regions for inter-cell ...
Bujar Krasniqi +7 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Maximal estimates for strong arithmetic means of Fourier series
Advanced Nonlinear StudiesIt is well-understood that partial sums of Fourier series for L 1 functions don’t necessarily converge to the original function in the pointwise-almost everywhere sense.
Wilson Bobby
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Computing Partial Eigenvalue Sum in Electronic Structure Calculations
, 1997 In this paper, we present an algorithm for computing a partial sum of eigenvalues of a large symmetric positive definite matrix pair. We show that this computational task is intimately connected to compute a bilinear form u T f(A)u for a properly ...
G. Golub +4 more
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Study on the Reliability Allocation Algorithm Based on Partial Squares Sum
, 2011 In this paper, it is first time that partial squares sum combined with orthogonal design according to the characteristics of quality assurance system, and applied to the reliability predicting and allocation, therefore, We may get the best reliability ...
An Jiang +5 more
core +1 more source
Journal of High Energy PhysicsBy incorporating the available leading-power results at O α s $$ \mathcal{O}\left({\alpha}_s\right) $$ and next-to-leading-power corrections at tree level, we compute the O α s 2 β 0 $$ \mathcal{O}\left({\alpha}_s^2{\beta}_0\right) $$ contribution to the
Yong-Kang Huang +4 more
doaj +1 more source
Partial Sums of Fourier Series [PDF]
Proceedings of the National Academy of Sciences, 1951 openaire +2 more sources