Results 91 to 100 of about 388,835 (376)

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

open access: yesAdvanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou   +16 more
wiley   +1 more source

Co-relation of coagulation profile with glycemic index in patients with type 2 diabetes

open access: yesJournal of Family Medicine and Primary Care
Background: Diabetes mellitus (DM) has emerged as a significant global concern that accounts for nearly 90% of type 2 DM cases worldwide and characterized by insulin resistance. Hyperglycemia in diabetes leads to increased fibrinogen levels and activates
Sushil Kumar   +5 more
doaj   +1 more source

The changes in the fibrinogen concentration and coagulation pathways in winter and summer in cattle [PDF]

open access: yesĀsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2013
Fibrinogen is an important coagulation factor and a positive acute phase protein and its levels increases in cases of inflammation infection and stress. The present research was done to determine whether the fibrinogen concentration, prothrombin time (PT)
ameneh khoshvaghti
doaj  

Evaluation of anticoagulant and thrombolytic activity of Berberis orthobotrys in animal model

open access: yesBangladesh Journal of Pharmacology, 2018
Fundamental to this research was the evaluation of anticoagulant and thrombolytic potential of Berberis orthobotrys using clotting time, prothrombin time and activated partial thromboplastin time performed at 2.5, 5, 10% concentration.
. Alamgeer   +3 more
doaj   +1 more source

Deep Learning Model for Predicting Operative Mortality After Total Gastrectomy: Analysis of the Japanese National Clinical Database (NCD)

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Deep learning‐based prediction model for operative mortality using the National Clinical Database (NCD). The model achieved a C‐statistic of 0.74. ABSTRACT Background Radical gastrectomy with lymph node dissection is the primary treatment for gastric cancer.
Ryosuke Fukuyo   +5 more
wiley   +1 more source

Establishing reference ranges and normal values for coagulation screening in healthy Indian male volunteers enrolled for a longitudinal study

open access: yesBiomedical and Biotechnology Research Journal, 2019
Background: The study was designed for establishing reference ranges and normal values for coagulation screening in healthy Indian male volunteers.
Rehan Ahmed   +8 more
doaj   +1 more source

Iptacopan for Immune Thrombocytopenia and Cold Agglutinin Disease: A Global Phase 2 Basket Clinical Trial

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Iptacopan is a first‐in‐class, oral, selective inhibitor of complement factor B that has demonstrated positive efficacy across several complement‐driven diseases. Here we evaluate the efficacy and safety of iptacopan monotherapy in adult patients with primary immune thrombocytopenia (ITP) and primary cold agglutinin disease (CAD). We performed
Alexander Röth   +13 more
wiley   +1 more source

Sex-Specific Associations between Thyroid Status, Inflammation and Hemostasis Biomarkers in Patients with Subacute Thyroiditis

open access: yesBiomedicines
Background: Subacute thyroiditis (SAT) is characterized by profound inflammation and fluctuations in thyroid hormones which may affect the hemostasis balance.
Jelena Vekic   +6 more
doaj   +1 more source

Study of Basic Coagulation Parameters among HIV Patients in Correlation to CD4 Counts and Art Status [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: HIV infection is known to cause coagulation abnormalities by various mechanism, especially during its late course. Aim: The objective of this study is to analyse platelet count, prothrombin time and activated partial thromboplastin time
R Thulasi Raman   +5 more
doaj   +1 more source

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