Results 111 to 120 of about 747,119 (356)

Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs [PDF]

, 2017
Increases in prothrombin time (PT) and international normalised ratio (INR) characterise acute liver injury (ALI) and failure (ALF), yet a wide heterogeneity in clotting abnormalities exists.
A Clauss, A Gatt, A Tripodi, A Zambruni, AF Riddell, AO Spiel, B Agarwal, B Agarwal, B Agarwal, DJ Antoine, DJ Antoine, E Gehrie, EA Sankey, FB Mayr, GC Hugenholtz, H Schochl, HJ Tsai, J Vaquero, JG O’Grady, JH Griffin, KC Lee, KC Lee, L Rinaldi, LA Baker, M Habib, M Senzolo, M Yamaguchi, MJ McPhail, P Chowdary, R Jalan, R Kanel von, RT Stravitz, RT Stravitz, SJ Deventer van, SJ Munoz, SR Ostrowski, T Lisman, T Lisman, TE Warkentin, V Rewari   +39 more
core   +3 more sources

Clot waveform analysis of prolonged activated partial thromboplastin time in various disorders

Indian Journal of Pathology and Microbiology
Introduction: The prolongation in APTT reflects various disorders affecting the blood coagulation system. Automated coagulation analyzers such as ACL TOP, help in evaluating the clotting cascade by displaying clot reaction curves or waveforms. The fibrin
Apeksha Kadu, Ami M. Shah, Hansa Goswami
doaj   +1 more source

On solvability of a partial integral equation in the space ${L_2(Ω\timesΩ)}$ [PDF]

arXiv, 2008
In this paper we investigate solvability of a partial integral equation in the space $L_2(\Omega\times\Omega),$ where $\Omega=[a,b]^\nu.$ We define a determinant for the partial integral equation as a continuous function on $\Omega$ and for a continuous kernels of the partial integral equation we give explicit description of the solution.
arxiv  

An infant with Kawasaki disease having gastrointestinal bleeding due to multiple gastric ulcers

Journal of General and Family Medicine, EarlyView.
Abstract Kawasaki disease (KD) is an acute systemic vasculitis managed mainly through intravenous immunoglobulin (IVIG), aspirin, and steroids. Although gastrointestinal symptoms are common, gastrointestinal bleeding is rare. We present the case of an 11‐month‐old girl with incomplete KD who developed severe gastrointestinal bleeding due to multiple ...
Takeru Kanazawa, Tomokazu Nakagami, Jyoji Yoshizawa, Yoshifusa Abe   +3 more
wiley   +1 more source

The frequency and timing of sepsis-associated coagulopathy in the neonatal intensive care unit

Frontiers in Pediatrics
IntroductionSepsis is a common cause of morbidity and mortality in the neonatal intensive care unit (NICU). The frequency and severity of sepsis-associated coagulopathy as well as its relationship to illness severity are unclear.MethodsWe performed a ...
Khyzer B. Aziz, Matthew Saxonhouse, Divya Mahesh, Kathryn E. Wheeler, James L. Wynn   +4 more
doaj   +1 more source

Platelet inhibitory effects of the Phase 3 anticancer and normal tissue cytoprotective agent, RRx-001. [PDF]

, 2018
The platelet inhibitory effects of the Phase 3 anticancer agent and nitric oxide (NO) donor, RRx-001, (1-bromoacetyl-3,3-dinitroazetidine) were examined ex vivo and compared with the diazeniumdiolate NO donor, diethylenetriamine NONOate (DETA-NONOate ...
Bryan Oronsky, Neil Oronsky, Pedro Cabrales, Santoro SA   +3 more
core   +1 more source

Pantethine therapy dramatically rescues end‐stage failing heart in a patient with deficiency of coenzyme A biosynthesis

ESC Heart Failure, EarlyView.
Violette Goetz, Bruno Lefort, Magalie Barth, Naïg Gueguen, Céline Bris, Emmanuelle Blanchard, Isabelle Benz‐de Bretagne, Hélène Blasco, Marine Tardieu, François Labarthe   +9 more
wiley   +1 more source

Trends in the Outcomes of Advanced Hepatobiliary‐Pancreatic Surgery: The Impact of a Nationwide Clinical Database and Surgeon Certification System

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background The Japanese Society of Hepatobiliary and Pancreatic Surgery has established a certification system for experienced surgeons. Evaluating its efficacy requires accounting for patient risk variations. The National Clinical Database (NCD) facilitates this using risk‐adjusted outcome measures to validate and compare surgical performance.
Takayuki Anazawa, Hiroyuki Yamamoto, Etsuro Hatano, Mitsukazu Gotoh, Masafumi Nakamura, Masayuki Ohtsuka, Itaru Endo   +6 more
wiley   +1 more source

Genetic Associations for Activated Partial Thromboplastin Time and Prothrombin Time, their Gene Expression Profiles, and Risk of Coronary Artery Disease [PDF]

, 2012
Activatedpartialthromboplastintime (aPTT) and prothrombintime (PT) are clinical tests commonly used to screen for coagulation-factor deficiencies. One genome-wide association study (GWAS) has been reported previously for aPTT, but no GWAS has been ...
Aaron R. Folsom, Adrian Tan, Alan J. Gow, Albert Tenesa, Andrew A. Hicks, Andrew D. Johnson, Andrew S. Plump, Ann Rumley, Aulchenko, Bezemer, Chen, Christine Schwienbacher, Claudia B. Volpato, Cosetta Minelli, Daniel Levy, David-Alexandre Tregouet, David J. Porteous, Deary, Eric Boerwinkle, Ewald, Fehrmann, Fourel, Gail Davies, Gandin, Ghosh, Gordon D.O. Lowe, Greenawalt, Greenwell, Hosoi, Houlihan, Hron, Ian J. Deary, Innocenti, Ireland, Ireland, Jackson, Jacobs, James S. Pankow, Jensen, John Gallacher, John M. Starr, John W.G. Yarnell, Jones, Kitchen, Lee, Li, Li, Li, Liu, Lorna M. Lopez, López-Sagaseta, Martin Gögele, Mary Cushman, Morange, Morelli, Murphy, Nena Matijevic, Nilesh J. Samani, Owens, Pattaro, Peter M. Visscher, Peter P. Pramstaller, Pierre-Emmanuel Morange, Preuss, Purcell, Reiner, Sainz, Saonli Basu, Scanavini, Schadt, Schunkert, Shigekiyo, Shigekiyo, Smith, Smith, Souto, Souto, Souto, Tang, Tiphaine Oudot-Mellakh, Trégouët, Tsuchida-Straeten, Valur Emilsson, Warren, Weihong Tang, White, Willer, Yarnell, Yoav Ben-Shlomo, Zakai, Zeller   +90 more
core   +1 more source

Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta, Matt Hall, Benjamin Masserano, Averi Wilson, Katherine Johnson, Clifford Chen, Lasya Challa, Harita Katragadda, Vineeta Mittal   +8 more
wiley   +1 more source