Hepatology Research, EarlyView.Abstract Aim Antithrombin (AT), a plasma protein with anticoagulant properties, has a long‐standing medical history, primarily for treatment of congenital AT deficiency. Accumulated clinical experiences suggest AT is a potential anticoagulant for thrombotic diseases. This study aimed to clarify the effectiveness, safety, and clinical significance of AT
Shoichi Matsutani +2 more
wiley +1 more source
Point-of-Care Testing for Prothrombin Time, but Not Activated Partial Thromboplastin Time, Correlates With Laboratory Methods in Patients Receiving Aprotinin or epsilon-Aminocaproic Acid While Undergoing Cardiac Surgery [PDF]
, 2002 Tak-Shun Choi +5 more
openalex +1 more source
Measuring Direct Oral Anticoagulant (DOAC) Levels: Applications, Limitations, and Future Directions
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction There are important challenges with the measurement and interpretation of direct oral anticoagulant (DOAC) anticoagulant effect including a lack of therapeutic ranges, inaccuracy of routinely available coagulation assays, lack of established thresholds for clinically significant effect, and uncertainty about how to apply the ...
Siraj Mithoowani +2 more
wiley +1 more source
Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley +1 more source
Characterization of the putative wobbly possum disease virus : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Virology at Massey University, Manawatū, New Zealand [PDF]
, 2017 The objective of this PhD was to characterise a marsupial arterivirus, termed wobbly possum disease virus (WPDV), and to confirm aetiological involvement of the virus in the development of a neurological disease of the Australian brushtail possum ...
Giles, Julia Christine
core
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction Argatroban is routinely monitored using activated partial thromboplastin time (APTT), with a recommended target range of 1.5–3.0 times. Although this range was established based on clinical trial data, including several APTT reagents, the differences in reactivity among APTT reagents remain unclear.
Osamu Kumano +6 more
wiley +1 more source
Effect of emicizumab-neutralizing antibodies on activated partial thromboplastin time-based clotting time test results in patients treated with emicizumab. [PDF]
Res Pract Thromb Haemost, 2023 Novembrino C +4 more
europepmc +1 more source
Heparin in Vitro Sensitivity of the Activated Partial Thromboplastin Time in Canine Plasma Depends on Reagent [PDF]
, 2003 Reinhard Mischke
openalex +1 more source
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction The International Society of Thrombosis and Hemostasis (ISTH) guidelines suggest a three‐step evaluation for the detection of lupus anticoagulant (LA), including screening, mixing, and confirmation. According to the guidelines, the LA assay based on activated partial thromboplastin time (APTT) should include an initial screening ...
Bárbara G. Barion +7 more
wiley +1 more source