Results 271 to 280 of about 353,583 (326)

Activated Partial Thromboplastin Time and Minor Coagulopathies

American Journal of Clinical Pathology, 1979
Five commercially available activated partial thromboplastin time (APTT) test systems were compared with the kaolin partial thromboplastin time (KPTT) method to determine sensitivity in detecting minor coagulation defects. All reagent systems detected severe factor VIII-, IX-, and XI-deficient hemophilia.
William E. Hathaway, Sherry L. Assmus, Robert R. Montgomery, A. Stephen Dubansky   +3 more
openaire   +3 more sources

The Partial Thromboplastin Time and Factor VIII Therapy

American Journal of Clinical Pathology, 1972
A large pseudotumor was removed from a hemophiliac patient, necessitating the use of long-term, high-dose therapy with factor VIII concentrate. The patient's activated partial thromboplastin time rarely normalized in spite of high factor VIII assay levels. In addition, other routine tests of coagulation became abnormal.
C. Jack Bark, Marshall J. Orloff
openaire   +3 more sources

Heparin and Partial Thromboplastin Time: an International Survey

British Journal of Haematology, 1980
Summary.The reliability of routine partial thromboplastin time (PTT) methods in the measurement of the anticoagulant effect of heparin has been assessed in a study involving over 300 hospitals in the U.K. and overseas. Commercial PTT methods were relatively insensitive to heparin, added in vitro, compared with the standardized PTT method tested by the ...
K.F. Yee, J. M. Thomson, L. Poller
openaire   +3 more sources

Abnormal activated partial thromboplastin time and malignancy

Scottish Medical Journal, 2011
Malignancy often results in clotting abnormalities. The aetiology of haemostasis problems in cancer is complex, and is still not completely understood. We describe a case of a patient with malignant mesothelioma, who was found to have elevated activated partial thromboplastin time, due to lupus anticoagulant.
M Delicata, H Hambley
openaire   +2 more sources

Effects of sugammadex on activated partial thromboplastin time and prothrombin time in healthy subjects.

International journal of clinical pharmacology and therapeutics, 2014
OBJECTIVES To assess the impact of sugammadex on activated partial thromboplastin time (APTT) and international normalized ratio for prothrombin time (PT(INR)) in healthy subjects and characterize the concentration-dependency of sugammadex effects on ...
P. De Kam, P. Grobara, M. Prohn, F. Höppener, C. Kluft, J. Burggraaf, R. B. Langdon, P. Peeters   +7 more
semanticscholar   +1 more source

The influence of free hemoglobin and bilirubin on heparin monitoring by activated partial thromboplastin time and anti-Xa assay.

Archives of Pathology & Laboratory Medicine, 2014
CONTEXT Elevated free hemoglobin (Hb) and bilirubinemia complicate extracorporeal membrane oxygenation and could affect unfractionated heparin (UH) therapy monitoring by anti-Xa assay and activated partial thromboplastin time (aPTT).
V. Kostousov, Kim T. Nguyen, Shilpa G Hundalani, J. Teruya   +3 more
semanticscholar   +1 more source

The partial thromboplastin time with kaolin. A simple screening test for first stage plasma clotting factor deficiencies.

American Journal of Clinical Pathology, 1961
The partial thromboplastin time (PPT) test consists of recalcifying plasma in the presence of a lipid reagent that supplies optimal platelet thromboplastic factor-like activity.
Robert R. Proctor, S. Rapaport
semanticscholar   +1 more source

Shortened activated partial thromboplastin time: causes and management

Blood Coagulation & Fibrinolysis, 2010
Throughout the long history of the hemostasis laboratory, and as an evaluation of the coagulation cascade, the results of the activated partial thromboplastin time (APTT) have primarily been considered as an index of loss-of-function and rarely as an index of gain-of-function.
LIPPI, Giuseppe, SALVAGNO, GIAN LUCA, Ippolito L, Franchini M, Favaloro E.J.   +4 more
openaire   +4 more sources

Correlation Between Activated Clotting Time and Activated Partial Thromboplastin Times

The Annals of Pharmacotherapy, 2002
OBJECTIVE: To evaluate the correlation between clotting time tests and heparin concentration, the correlation between activated clotting time (ACT) and activated partial thromboplastin time (aPTT) results, and to compare the clinical decisions based on ACT results with those based on aPTT results.
Susan J. Westley, John M. Koerber, Sandra N. Nowak, Maureen A. Smythe, Mamtha Balasubramaniam, Robert L Begle, Joan C. Mattson   +6 more
openaire   +2 more sources

Extremely Shortened Activated Partial Thromboplastin Times

JAMA: The Journal of the American Medical Association, 1980
To the Editor.— The presence of a hypercoagulable state in patients with a shortened activated partial thromboplastin time (APTT) as manifested by the clinical association with an increased incidence of thromboembolic disease has previously been reported by Hume, 1 Gallus et al, 2 Pilgeram, 3 McKenna et al, 4 and McKenna et al.
openaire   +3 more sources