Results 291 to 300 of about 1,015,424 (347)
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Biological variation estimates of prothrombin time, activated partial thromboplastin time, and fibrinogen in 28 healthy individuals

International Journal of Laboratory Hematology, 2018
Although tests of global hemostasis prothrombin time (PT) and activated partial thromboplastin time (aPTT) should not be used for prediction of bleeding risk, these tests are often used by many clinicians in daily practice particularly as a preoperative ...
M. Falay   +7 more
semanticscholar   +1 more source

Comparison of Anti-Xa and Activated Partial Thromboplastin Time Monitoring for Heparin Dosing in Patients With Cirrhosis

Therapeutic Drug Monitoring, 2015
Backgroud: Cirrhosis of the liver results in complex hemostatic changes that place patients at risk for both bleeding and thrombotic events. This study evaluates the adverse effects of anticoagulation with unfractionated heparin among patients with ...
A. Fuentes   +4 more
semanticscholar   +1 more source

Routine Use of the Prothrombin and Partial Thromboplastin Times

JAMA: The Journal of the American Medical Association, 1989
The prothrombin time (PT) and activated partial thromboplastin time (APTT) tests are often routinely ordered for hospitalized patients. Ordering patterns and clinical indications for the PT and APTT tests on the medical service at a teaching hospital were studied. Eighty-one percent of all patients admitted to the medical service had a PT and APTT test
Stephen Erban, Kinman Jl, Schwartz Js
openaire   +3 more sources

Activated Partial Thromboplastin Time and Minor Coagulopathies

American Journal of Clinical Pathology, 1979
Five commercially available activated partial thromboplastin time (APTT) test systems were compared with the kaolin partial thromboplastin time (KPTT) method to determine sensitivity in detecting minor coagulation defects. All reagent systems detected severe factor VIII-, IX-, and XI-deficient hemophilia.
William E. Hathaway   +3 more
openaire   +3 more sources

The Partial Thromboplastin Time and Factor VIII Therapy

American Journal of Clinical Pathology, 1972
A large pseudotumor was removed from a hemophiliac patient, necessitating the use of long-term, high-dose therapy with factor VIII concentrate. The patient's activated partial thromboplastin time rarely normalized in spite of high factor VIII assay levels. In addition, other routine tests of coagulation became abnormal.
C. Jack Bark, Marshall J. Orloff
openaire   +3 more sources

Heparin and Partial Thromboplastin Time: an International Survey

British Journal of Haematology, 1980
Summary.The reliability of routine partial thromboplastin time (PTT) methods in the measurement of the anticoagulant effect of heparin has been assessed in a study involving over 300 hospitals in the U.K. and overseas. Commercial PTT methods were relatively insensitive to heparin, added in vitro, compared with the standardized PTT method tested by the ...
K.F. Yee, J. M. Thomson, L. Poller
openaire   +3 more sources

Evaluation of the activated clotting time and activated partial thromboplastin time for the monitoring of heparin in adult extracorporeal membrane oxygenation patients

Perfusion, 2014
Introduction: Historically, the activated clotting time (ACT) has been the preferred monitoring test of the heparin effect in extracorporeal membrane oxygenation (ECMO) patients.
S. Atallah   +5 more
semanticscholar   +1 more source

Evaluation of the activated partial thromboplastin time assay for clinical monitoring of PEGylated recombinant factor VIII (BAY 94‐9027) for haemophilia A

Haemophilia, 2014
Patients with haemophilia (PWH) are usually monitored by the one‐stage activated partial thromboplastin time (aPTT) factor VIII (FVIII) assay. Different aPTT activators may affect clotting time (CT) and FVIII:C levels in patients treated with PEGylated ...
Jian-Ming Gu   +8 more
semanticscholar   +1 more source

Abnormal activated partial thromboplastin time and malignancy

Scottish Medical Journal, 2011
Malignancy often results in clotting abnormalities. The aetiology of haemostasis problems in cancer is complex, and is still not completely understood. We describe a case of a patient with malignant mesothelioma, who was found to have elevated activated partial thromboplastin time, due to lupus anticoagulant.
M Delicata, H Hambley
openaire   +2 more sources

The influence of free hemoglobin and bilirubin on heparin monitoring by activated partial thromboplastin time and anti-Xa assay.

Archives of Pathology & Laboratory Medicine, 2014
CONTEXT Elevated free hemoglobin (Hb) and bilirubinemia complicate extracorporeal membrane oxygenation and could affect unfractionated heparin (UH) therapy monitoring by anti-Xa assay and activated partial thromboplastin time (aPTT).
V. Kostousov   +3 more
semanticscholar   +1 more source

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