Results 301 to 310 of about 1,015,424 (347)

Effects of sugammadex on activated partial thromboplastin time and prothrombin time in healthy subjects.

International journal of clinical pharmacology and therapeutics, 2014
OBJECTIVES To assess the impact of sugammadex on activated partial thromboplastin time (APTT) and international normalized ratio for prothrombin time (PT(INR)) in healthy subjects and characterize the concentration-dependency of sugammadex effects on ...
P. De Kam, P. Grobara, M. Prohn, F. Höppener, C. Kluft, J. Burggraaf, R. B. Langdon, P. Peeters   +7 more
semanticscholar   +1 more source

The effect of dabigatran on the activated partial thromboplastin time and thrombin time as determined by the Hemoclot thrombin inhibitor assay in patient plasma samples

Thrombosis and Haemostasis, 2013
Summary Dabigatran is an oral direct thrombin inhibitor that does not require routine laboratory monitoring. However, an assessment of its anticoagulant effect in certain clinical settings is desirable.
G. Hapgood, J. Butler, E. Malan, S. Chunilal, Huyen A Tran   +4 more
semanticscholar   +1 more source

Shortened activated partial thromboplastin time: causes and management

Blood Coagulation & Fibrinolysis, 2010
Throughout the long history of the hemostasis laboratory, and as an evaluation of the coagulation cascade, the results of the activated partial thromboplastin time (APTT) have primarily been considered as an index of loss-of-function and rarely as an index of gain-of-function.
LIPPI, Giuseppe, SALVAGNO, GIAN LUCA, Ippolito L, Franchini M, Favaloro E.J.   +4 more
openaire   +4 more sources

The partial thromboplastin time with kaolin. A simple screening test for first stage plasma clotting factor deficiencies.

American Journal of Clinical Pathology, 1961
The partial thromboplastin time (PPT) test consists of recalcifying plasma in the presence of a lipid reagent that supplies optimal platelet thromboplastic factor-like activity.
Robert R. Proctor, S. Rapaport
semanticscholar   +1 more source

Extremely Shortened Activated Partial Thromboplastin Times

JAMA: The Journal of the American Medical Association, 1980
To the Editor.— The presence of a hypercoagulable state in patients with a shortened activated partial thromboplastin time (APTT) as manifested by the clinical association with an increased incidence of thromboembolic disease has previously been reported by Hume, 1 Gallus et al, 2 Pilgeram, 3 McKenna et al, 4 and McKenna et al.
openaire   +3 more sources

Correlation Between Activated Clotting Time and Activated Partial Thromboplastin Times

The Annals of Pharmacotherapy, 2002
OBJECTIVE: To evaluate the correlation between clotting time tests and heparin concentration, the correlation between activated clotting time (ACT) and activated partial thromboplastin time (aPTT) results, and to compare the clinical decisions based on ACT results with those based on aPTT results.
Susan J. Westley, John M. Koerber, Sandra N. Nowak, Maureen A. Smythe, Mamtha Balasubramaniam, Robert L Begle, Joan C. Mattson   +6 more
openaire   +2 more sources

Influence of temperature and storage duration on measurement of activated partial thromboplastin time, D‐dimers, fibrinogen, prothrombin time and thrombin time, in citrate‐anticoagulated whole blood specimens

International Journal of Laboratory Hematology, 2013
We report the effect of temperature and storage duration on a range of haematological analytes: activated partial thromboplastin time (APTT), D‐dimers, fibrinogen (Fbg), prothrombin time (PT) and thrombin time (TT).
Y. Zhao, G. Lv
semanticscholar   +1 more source

Prothrombin Time and Partial Thromboplastin Time Assay Considerations

Clinics in Laboratory Medicine, 2009
Prothrombin times and activated partial thromboplastin times have long been used as tests of overall ("global") clotting function. Laboratory coagulation testing issues should be at the forefront of the reader's consciousness whenever critically evaluating and extrapolating published study conclusions reliant on the results of these tests.
openaire   +3 more sources

Coagulation Studies: Prothrombin Time, Partial Thromboplastin Time, Bleeding Time

Emergency Medicine Clinics of North America, 1986
Three coagulation tests available in the emergency department are described in this article. Methods, results, and implications in the bleeding patient are reviewed.
Glenn C. Hamilton, Mark G. Angelos
openaire   +3 more sources

Partial Thromboplastin Time Reagents: Another Look

Laboratory Medicine, 1985
Ellagic acid and micronized silica, respectively, are the activating agents in two commonly used commercial partial thromboplastin time reagents. The two reagents were compared for their ability to detect partial deficiencies of clotting factors. The normal ranges for each were first determined using one semiautomated clot-detecting machine.
Lorraine Bauman, Theodore S. Zimmerman
openaire   +2 more sources