Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Hepatology, EarlyView., 2022 Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source
Hemostatic activities of methanol leaf extracts of Croton megalocarpus Hutch and Lantana camara Linn
Journal of Advanced Biotechnology and Experimental Therapeutics, 2021 Hemostasis is the natural mechanism by which blood is kept in a fluid state in circulation with the ability to cause clotting at an injury site. The effects of Croton megalocarpus Hutch and Lantana camara Linn plants leaves on blood coagulation has not ...
Hezron Mutisya Muindi +2 more
doaj +1 more source
A perioperative uncontrollable bleeding in an elderly patient with acquired hemophilia A: a case report [PDF]
, 2013 Acquired hemophilia A should be taken into account in the differential diagnosis of perioperative bleeding in patients without any apparent reason for activated partial thromboplastin time ...
CORTEGIANI, Andrea +6 more
core +1 more source
JAI (Jurnal Anestesiologi Indonesia), 2009 Latar belakang: Pasien dengan operasi besar yang beresiko terjadi perdarahan semakin meningkat setiap tahun. HES dengan berat molekul besar mempertahankan hemodinamik lebih baik tetapi mengganggu faktor koagulasi.
Hari Hendriarto Satoto +2 more
doaj +1 more source
Biological evaluation of the effect of sugammadex on hemostasis and bleeding [PDF]
Korean Journal of Anesthesiology, 2015 BackgroundNotification of sugammadex has been supplemented with a section on hemostasis, including a longer clotting time in the first minutes following injection, without any documented clinical consequences.
Julien Raft +4 more
doaj +1 more source
Performance Evaluation of Four Activated Partial Thromboplastin Time Reagents
Pharmacology and Clinical Pharmacy Research, 2018 Activated Partial Thromboplastin Time (APTT) is a hematological examination to identify hemostatic abnormalities. This study aimed to compare the performance evaluation of four APTT reagents, i.e., CK Prest, Pathromtin SL, Actin SL, and Cephascreen.
Peppi Z. Yuzaqi +2 more
doaj +1 more source
Canine reference intervals for coagulation markers using the STA Satellite and the STA-R Evolution analyzers [PDF]
, 2010 The aim of the current study was to determine canine reference intervals for prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen, and antithrombin (AT) according to international recommendations. The STA Satellite coefficients
Braun, Jean-Pierre +5 more
core +1 more source
Timing and volume of fluid administration for patients with bleeding [PDF]
, 2003 Original article can be found at: http://www3.interscience.wiley.com Copyright John Wiley & Sons. ‘This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2003, Issue 3.
Bunn, Frances, Kwan, I., Roberts, I.
core +1 more source
Aromatic Amines Exert Contrasting Effects on the Anticoagulant Effect of Acetaldehyde upon APTT
Advances in Hematology, 2014 The pharmacological effects of amphetamine, procaine, procainamide, DOPA, isoproterenol, and atenolol upon activated partial thromboplastin time in the absence and presence of acetaldehyde have been investigated.
La'Teese Hall +2 more
doaj +1 more source
Safety of Needle Electromyography in Critically Ill Patients [PDF]
, 2020 Introduction: To evaluate the safety of needle electromyography (EMG) in critically ill intensive care unit (ICU) patients who are on anticoagulants and have comorbidities that increase the risk of bleeding and infections.
Bollu, Pradeep +5 more
core +2 more sources