Results 51 to 60 of about 388,835 (376)

A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X. [PDF]

, 2008
BackgroundActivated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is
Arruda, VR, Chu, K, Golden, JA, Herzog, RW, High, KA, Labosky, PA, Margaritis, P, Tai, SJ   +7 more
core   +2 more sources

Guidelines on fibrinogen assays [PDF]

, 2003
No abstract ...
Becker, Blanco, Blomback, Cambas, Chantarangkul, Chantarangkul, Chitolie, Chitolie, Clauss, Cremer, Cushman, De Cristofaro, De Maat, De Metz, Eliasson, Gaffney, Gordon D. O. Lowe, Hantgan, Haverkate, Hoffmann, Humphries, Ian J. Mackie, Jacobsson, Kitchen, Kluft, Lawrie, Lowe, Lowe, Ludlam, Machin, Mackie, Marder, MDA, MDA, Natelson, NCCLS, Nieuwenhuizen, Oosting, Palareti, Rampling, Ratnoff, Rosenson, Rossi, Samuel J. Machin, Steven Kitchen, Swain, Sweetnam, Sweetnam, Thompson, Van Der Bom, Vermylen, Whicher, World Health Organisation Report   +52 more
core   +1 more source

Prothrombine and activated partial thromboplastin time are prolonged in hepatic cirrhosis

Universa Medicina, 2016
Background Chronic hepatitis and hepatic cirrhosis are chronic liver diseases that cause disorders of liver function, such as the formation of platelets and coagulation factors (prothrombin time/PT and activated partial thromboplastin time/APTT ...
Edward Kurnia Setiawan Limijadi, Lisyani Budi Suromo, Imam Budiwiyono   +2 more
doaj   +1 more source

Association of coagulation profile with microvascular complications and glycemic control in type 2 diabetes mellitus – a study at a tertiary care center in Delhi

Hematology, Transfusion and Cell Therapy, 2019
Introduction: Type 2 diabetes mellitus, characterized by insulin resistance, corresponds to approximately 90% of cases of diabetes worldwide. Hyperglycemia in diabetes contributes to hyperfibrinogenemia and activates the coagulation cascade thereby ...
Charu Agarwal, Kashish Bansal, Mukta Pujani, Kanika Singh, Varsha Chauhan, Deepshikha Rana, Shveta Lukhmana   +6 more
doaj   +1 more source

Evaluation of Antifactor-Xa Heparin Assay and Activated Partial Thromboplastin Time Values in Patients on Therapeutic Continuous Infusion Unfractionated Heparin Therapy

Clinical and applied thrombosis/hemostasis, 2019
Clinical uncertainty exists regarding which assay should be designated as the standard monitoring coagulation test for intravenous unfractionated heparin (UFH).
K. McLaughlin, J. Rimsans, K. Sylvester, J. Fanikos, D. Dorfman, Patricia Senna, J. Connors, S. Goldhaber   +7 more
semanticscholar   +1 more source

Mixing Studies in Patients With Prolonged Activated Partial Thromboplastin Time or Prothrombin Time.

Anesthesia and Analgesia, 2019
BACKGROUND Patients presenting for surgery may have isolated or combined prolonged activated partial thromboplastin time (aPTT) and/or prothrombin time (PT).
H. Benzon, M. Park, R. McCarthy, M. Kendall, P. Lindholm   +4 more
semanticscholar   +1 more source

Intraoperative blood transfusions in highly alloimmunized patients undergoing orthotopic liver transplantation. [PDF]

, 1989
Intraoperative blood requirements were analyzed in patients undergoing primary orthotopic liver transplantation and divided into two groups on the basis of panel reactive antibody of pretransplant serum measured by lymphocytotoxicity testing.
Duquesnoy, RJ, Esquivel, CD, Kang, YG, Marino, IR, Starzl, TE, Weber, T   +5 more
core   +1 more source

Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]

, 2017
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila, Eskandani, Morteza, Farhoudi, Mehdi, Mohammadian, Reza, Rafi, Mohammad, Zamanlu, Masumeh   +5 more
core   +2 more sources

An Evaluation of Hemostatic Abnormalities in Patients With Hemophilia According to the Activated Partial Thromboplastin Time Waveform

Clinical and applied thrombosis/hemostasis, 2018
The usefulness of the waveform of activated partial thromboplastin time (APTT) in various diseases has been evaluated in recent years. The APTT waveform was examined in patients with hemophilia and patients positive for lupus anticoagulant (LA).
Haruna Katayama, Takeshi Matsumoto, H. Wada, N. Fujimoto, Junki Toyoda, Y. Abe, K. Ohishi, Y. Yamashita, M. Ikejiri, K. Habe, N. Katayama   +10 more
semanticscholar   +1 more source

The Central role of KNG1 gene as a genetic determinant of coagulation pathway-related traits: Exploring metaphenotypes [PDF]

, 2016
Traditional genetic studies of single traits may be unable to detect the pleiotropic effects involved in complex diseases. To detect the correlation that exists between several phenotypes involved in the same biological process, we introduce ...
Brunel, Helena, Martin-Fernandez, Laura, Martinez Perez, Angel, Massanet, Raimon, Perera Lluna, Alexandre, Soria, José Manuel, Souto, Juan Carlos, Ziyatdinov, Andrey   +7 more
core   +4 more sources