Randomized double-blind placebo-controlled trial of 40 mg/day of atorvastatin in reducing the severity of sepsis in ward patients (ASEPSIS Trial) [PDF]
Introduction: Several observational studies suggest that statins modulate the pathophysiology of sepsis and may prevent its progression. The aim of this study was to determine if the acute administration of atorvastatin reduces sepsis progression in ...
Barnett, A. H.+11 more
core +3 more sources
The partial thromboplastin time: reply [PDF]
Bjarne Østerud+2 more
openaire +7 more sources
Crotalus atrox venom preconditioning increases plasma fibrinogen and reduces perioperative hemorrhage in a rat model of surgical brain injury. [PDF]
Perioperative bleeding is a potentially devastating complication in neurosurgical patients, and plasma fibrinogen concentration has been identified as a potential modifiable risk factor for perioperative bleeding.
Applegate, Richard+12 more
core +1 more source
Evaluation of coagulation disorders and iron deficiency in women with heavy menstrual bleeding
Abstract Objective To explore the incidence of congenital bleeding disorders (CBD), which may result in anemia, in a large cohort of women referred for heavy menstrual bleeding (HMB) in a specialized gynecologic unit. Methods Between January 2022 and January 2024, all women referred for HMB were screened.
Lucia Rugeri+8 more
wiley +1 more source
Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis. [PDF]
Protease-activated receptor (PAR)-1 is a cellular receptor for thrombin that is activated after proteolytic cleavage. The contribution of PAR-1 to inflammatory cell-mediated renal injury was assessed in murine crescentic glomerulonephritis (GN).
Bernatowicz+33 more
core +3 more sources
Complications were common but mostly minor following ultrasound‐guided percutaneous kidney biopsy. Older age, obesity, and smoking were independently associated with a reduced risk of complications, including hematoma. These findings highlight the overall safety of the procedure and support individualized risk assessment based on patient ...
Sehyun Jung+5 more
wiley +1 more source
Expert Perspective: Hematologic Malignancies and Vasculitis
Arthritis &Rheumatology, EarlyView.
Michelle L. Robinette, Hetty E. Carraway
wiley +1 more source
An infant with Kawasaki disease having gastrointestinal bleeding due to multiple gastric ulcers
Abstract Kawasaki disease (KD) is an acute systemic vasculitis managed mainly through intravenous immunoglobulin (IVIG), aspirin, and steroids. Although gastrointestinal symptoms are common, gastrointestinal bleeding is rare. We present the case of an 11‐month‐old girl with incomplete KD who developed severe gastrointestinal bleeding due to multiple ...
Takeru Kanazawa+3 more
wiley +1 more source
Wernicke encephalopathy observed in a cancer patient receiving terminal‐stage home care
Abstract We report an 80 year old man in the terminal stage of cancer receiving home care. On the 18th day after starting home care, he experienced a sudden onset of impaired consciousness, unsteadiness of gait, and ophthalmoplegia. Based on the clinical symptoms and a prolonged loss of appetite, Wernicke encephalopathy (WE) was suspected. Thiamine 100
Minoru Saiki+4 more
wiley +1 more source
Abstract Mesenteric hematomas (MHs) are relatively rare and are characterized by localized bleeding in the mesenteric vascular tree presenting with abdominal pain, vomiting, abdominal distension, masses, and hypotension. We report a case of a MH which was incidentally found in a 10‐year‐old patient with a new diagnosis of ulcerative colitis (UC).
Breanna Brown+2 more
wiley +1 more source