Background: Prothrombin time (PT) and activated partial thromboplastin time (APTT) are the tests used in the investigation and monitoring of hemostatic disorders. Plasma is used to perform these tests immediately or stored for later use.
Mohammed A Ndakotsu +4 more
doaj +1 more source
Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis. [PDF]
Protease-activated receptor (PAR)-1 is a cellular receptor for thrombin that is activated after proteolytic cleavage. The contribution of PAR-1 to inflammatory cell-mediated renal injury was assessed in murine crescentic glomerulonephritis (GN).
Bernatowicz +33 more
core +3 more sources
Diagnosis of antiphospholipid syndrome following snakebite
Isolated prolongation of activated partial thromboplastin time (aPTT) is an exceedingly rare finding in the event of a snakebite from a haemotoxic snake. Herein, we present the case of a 25-year-old asymptomatic female following snakebite.
Mahalingeshwara Bhat +4 more
doaj +1 more source
Hydroxyethyl starch (HES) is a colloid administered frequently for intravascular volume expansion during perioperative period. Impairment of haemostasis have been reported during HES administration, but the volume of solution administered was usually ...
Sarah Puspita Atmaja +5 more
doaj +1 more source
Idarucizumab for Dabigatran Reversal - Full Cohort Analysis. [PDF]
BACKGROUND: Idarucizumab, a monoclonal antibody fragment, was developed to reverse the anticoagulant effect of dabigatran. METHODS: We performed a multicenter, prospective, open-label study to determine whether 5 g of intravenous idarucizumab would be ...
Bernstein, Richard A. +20 more
core +1 more source
A performance evaluation of commercial fibrinogen reference preparations and assays for Clauss and PT-derived fibrinogen [PDF]
The wide availability of fibrinogen estimations based on the prothrombin time (PT-Fg) has caused concern about the variability and clinical utility of fibrinogen assays.
Gaffney, P.J. +9 more
core +1 more source
The main ingredient in the daily salad dish is the leaves of Lactuca sativa, while the stems are usually discarded and not eaten. This study was conducted to compare the stems and leaves of two selected L. sativa varieties (L. sativa var.
Hanin Nafed Mughrbi +2 more
doaj +1 more source
A thoracic-epidural granulocytic sarcoma case that was diagnosed preceding the onset of and that recurred co-incidental to acute promyelocytic leukemia, which developed after surgical treatment. [PDF]
Granulocytic sarcoma or chloroma is a tumor seen in myelocytic leukemia. Spinal epidural onset is rare and is generally seen before or together with the onset of myelocytic leukemia.
Bayraktaroglu, Taner +6 more
core +1 more source
Effect of carbamazepine and levetiracetam on coagulation parameters: Prothrombin time, activated partial thromboplastin time, D-dimer, and fibrinogen levels [PDF]
Background: Epilepsy is a prevalent neurological disorder, and evaluating its treatment strategies is highly significant. This study aimed to compare the effects of monotherapy with carbamazepine and levetiracetam on the results of coagulation tests ...
Li Jiaohui, Zhong Chengyun, Bian Guanji
doaj +1 more source
What’s new about sample quality in routine coagulation testing? [PDF]
Today, laboratories are very much different than they were decades ago. They have improved instruments to work with, multiple off-site collection points, more competent personnel, a greater analyte panel and quality requirements for those analytes ...
Freitas, Francisco
core

