Results 71 to 80 of about 665,193 (301)
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Key Assignment Scheme with Authenticated Encryption
IACR Transactions on Symmetric Cryptology, 2018 The Key Assignment Scheme (KAS) is a well-studied cryptographic primitive used for hierarchical access control (HAC) in a multilevel organisation where the classes of people with higher privileges can access files of those with lower ones.
Suyash Kandele, Souradyuti Paul
doaj +1 more source
The morphology of partially ordered sets
Journal of Combinatorial Theory, Series A, 1974 DEFINITION. XC gn is called a set of incomparable elements if A, B E X and A C B imply A = B. Then Sperner’s Theorem -maxx / X 1 = (,J,,), where X ranges over all sets of incomparable elements in .?3,, . The standard proof of Sperner’s theorem (see Harper-Rota [lo]) is based upon two properties of an , unimodality and matching.
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FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Geometries on partially ordered sets
Journal of Combinatorial Theory, Series B, 1980 AbstractGeometries on finite partially ordered sets extend the concept of matroids on finite sets to partially ordered sets. Geometries are defined in terms of closure operators on partially ordered sets. The lattice of closed sets is semimodular, and every finite semimodular lattice is isomorphic to the lattice of closed sets of some geometry.
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Continuity in Partially Ordered Sets [PDF]
International Journal of Mathematics and Mathematical Sciences, 2008 The notion of a continuous domain is generalized to include posets which are not dcpos and in which the set of elements way below an element is not necessarily directed. We show that several of the pleasing algebraic and topological properties of domains carry over to this setting.
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Protein kinase FAM20C—when subcellular localization matters
FEBS Letters, EarlyView.FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source
Real-Valued Functions on Partially Ordered Sets [PDF]
, 1953 Seymour Ginsburg
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Inferring microRNA regulation of mRNA with partially ordered samples of paired expression data and exogenous prediction algorithms. [PDF]
PLoS ONE, 2012 MicroRNAs (miRs) are known to play an important role in mRNA regulation, often by binding to complementary sequences in "target" mRNAs. Recently, several methods have been developed by which existing sequence-based target predictions can be combined with
Brian Godsey, Diane Heiser, Curt Civin
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On the dimension of partially ordered sets
Journal of Combinatorial Theory, Series A, 1977 AbstractA generalization of the concept of dimension of a poset, the stable dimension, is introduced, and it is shown that there is a simple procedure for determining its value. No such procedure is known for the dimension itself. The main theorem shows that the stable dimension is equal to the maximum number of elements in a pair of antichains of the ...
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