Results 71 to 80 of about 9,689,082 (347)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Participative planning and information flow within management control

open access: yesZeszyty Teoretyczne Rachunkowości, 2016
The paper examines the relationships between two different approaches to planning processes (participa- tive and non-participative) and information flows within management control in companies. It augments the existing theoretical and empirical research
Tomasz Dyczkowski, Joanna Dyczkowska
doaj  

A Multiple Criteria Decision Making Approach to Designing Teaching Plans in Higher Education Institutions

open access: yesMathematics, 2020
The involvement of competences in the teaching–learning planning process in Higher Education is essential for their success in the European Higher Education Area. This study presents a participatory multi-criteria model based on Voting Analytic Hierarchy
Pilar Laguna-Sánchez   +3 more
doaj   +1 more source

Do it Right or Not at All: A Longitudinal Evaluation of a Conflict Managment System Implementation [PDF]

open access: yes, 2017
We analyzed an eight-year multi-source longitudinal data set that followed a healthcare system in the Eastern United States as it implemented a major conflict management initiative to encourage line managers to consistently perform Personal Management ...
Boss, Alan D   +4 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

What are the Key Competencies and Skills Required for Leaders in China for the Greatest ROI? [PDF]

open access: yes, 2015
Developing a leadership pipeline was the number one strategic business challenge in the American Chamber of Commerce Shanghai 2010 survey, even ahead of increasing market share and new innovations.
Kovack, Kasey S
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Simuler pour changer la conception et les rapports sociaux de conception du travail : un commentaire sur les dispositifs de simulation de l’activité dans les organisations

open access: yesActivités, 2018
The article discusses the contributions made to this issue on activity simulation. Focusing on the simulation of activity within organizations, it argues that the methods in question potentially affect power relations in change management processes.
Pascal Ughetto
doaj   +1 more source

What are the Key Practices that STEM & Manufacturing based Companies are Deploying to Drive Improvements in the Diversity of their Workforce? [PDF]

open access: yes, 2015
Studies have shown that approximately 67% of U.S. manufacturing companies are currently facing a worker shortage. This rate is dramatically higher than that of other private firms in the U.S. (See Appendix A).
Hackett, Alison
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

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