Results 71 to 80 of about 441,090 (336)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
New Media and Youth Political Action [PDF]
, 2012 To rigorously consider the impact of new media on the political and civic behavior of young people, The MacArthur Research Network on Youth and Participatory Politics (YPP) developed and fielded one of the first large-scale, nationally representative ...
Benjamin Bowyer +4 more
core
The challenges of participatory research with 'tech-savvy' youth [PDF]
, 2010 This paper focuses on participatory research and how it can be understood and employed when researching children and youth. The aim of this paper is to provide a theoretically and empirically grounded discussion of participatory research methodologies ...
Giardina, Natasha +2 more
core +2 more sources
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
In abundance: Networked participatory practices as scholarship
International Review of Research in Open and Distributed Learning, 2015 In an era of knowledge abundance, scholars have the capacity to distribute and share ideas and artifacts via digital networks, yet networked scholarship often remains unrecognized within institutional spheres of influence.
Bonnie E Stewart
doaj +1 more source
Understanding Participatory Culture for Teenagers with Autism Spectrum Disorder [PDF]
, 2021 Cendera Rizky Anugrah Bangun
openalex +1 more source
Los Angeles County Arts Commission: Public Engagement in the Arts - A Review of Recent Literature [PDF]
, 2016 Do all Americans have equal access to the arts? Are the arts accessible and inclusive for all communities? National rates of arts participation as measured by attendance at live benchmark events have been trending down for the past few decades ...
Bronwyn Mauldin, Stephanie N. Stallings
core
Creating participatory writing cultures in UK higher education [PDF]
, 2011 One particularly difficult area for higher education students is writing appropriately for their respective disciplines. As writing is a social, cultural and dialogic act, writing support should create learning events that will allow for useful social ...
Clughen, L, Hardy, C
core +2 more sources
Between empowerment and abuse: citizen participation beyond the post-democratic turn [PDF]
, 2020 In this special issue on “Democratization beyond the Post-Democratic Turn. Political Participation between Empowerment and Abuse”, we have explored changing understandings of participation in contemporary Western representative democracies through the ...
Butzlaff, Felix
core +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source