Results 71 to 80 of about 441,738 (307)

Serialized Participatory Culture: The Digital Transformation of Youth Audiences

Observatorio (OBS*), 2012
Digital technologies are transforming audiences and media practices and in a context of serialization this paper wants to make the case for television series as much of the attention from the industry and the academy is drawn by music and cinema neglecting the effects on television viewing.
Ganito, Carla, Burnay, Catarina Duff, Ferreira, Cátia   +2 more
openaire   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

The phenomenon of participatory culture in network communication and its educational potential

Вестник университета
A new cultural phenomenon that has been little explored by Russian scientists – the culture of complicity, the essence of which consists in joint development and creation of digital content by members of a virtual community united by interests, standards
L. V. Kozhevnikova, I. Ye. Starovoytova
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Memetic performance and participatory spectacle: audience ritual in the 2025 Minecraft movie

Frontiers in Communication
In 2025, the release of the Minecraft movie triggered a wave of youth-driven audience participation centered on the meme reference “chicken jockey,” which escalated into viral, in-theater performances.
Dag Øivind Madsen
doaj   +1 more source

Creating participatory writing cultures in UK higher education [PDF]

, 2011
One particularly difficult area for higher education students is writing appropriately for their respective disciplines. As writing is a social, cultural and dialogic act, writing support should create learning events that will allow for useful social ...
Clughen, L, Hardy, C
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

‘New’ literacies: technologies and values ‘New’ literacies: technologies and values

Revista Teknokultura, 2012
It is too easy to make light of ‘new literacies’ by saying things like: “Well, there are always newer ones coming along”. Such remarks suggest new literacies have a similar kind of life trajectory to an automobile: new in 2009, semi-new in 2010, and old ...
Michele Knobel, Colin Lankshear
doaj  

Exploring Participatory Design Methods to Engage with Arab Communities [PDF]

, 2018
ArabHCI is an initiative inaugurated in CHI17 SIG Meeting that brought together 45+ HCI Arab and non-Arab researchers/practitioners who are conducting/interested in HCI within Arab communities.
Alabdulqader, Ebtisam, Dray, Susan M., Khamis, Mohamed, Lazem, Shaimaa   +3 more
core   +1 more source