Results 101 to 110 of about 758,673 (282)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Experiences from patients in mental healthcare accessing their electronic health records: results from a cross-national survey in Estonia, Finland, Norway, and Sweden

BMC Psychiatry
Background Patients’ online record access (ORA) enables patients to read and use their health data through online digital solutions. One such solution, patient-accessible electronic health records (PAEHRs) have been implemented in Estonia, Finland ...
A.J. Fagerlund, Annika Bärkås, A. Kharko, C.R. Blease, J. Hagström, I. Huvila, I. Hörhammer, B. Kane, E. Kristiansen, S. Kujala, J. Moll, H. Rexhepi, I. Scandurra, S. Simola, H. Soone, B. Wang, R.M. Åhlfeldt, M. Hägglund, M.A. Johansen   +18 more
doaj   +1 more source

Big data security & individual (psychological) resilience: A review of social media risks and lessons learned from Indonesia

Array
This research aims to reduce social media security risks and develop best practices to help governments address social media security risks more effectively. This research begins by reviewing the different discussions in the literature about social media
Abdillah Abdillah, Ida Widianingsih, Rd Ahmad Buchari, Heru Nurasa   +3 more
doaj   +1 more source

From the Editor's Desk

Journal of Extension Education, 2019
Editorial of Journal of Extension Education 30(4)
D PUTHIRA PRATHAP
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Youth Reproductive Health in Nepal: Is Participation the Answer? [PDF]

, 2004
Discusses the processes and results of a multi-year research study by ICRW, EngenderHealth, and Nepali partners, which tested the effectiveness of the participatory approach in defining and addressing the reproductive health concerns of ...
Anju Malhotra, Manisha Mehta, Sanyukta Mathur   +2 more
core  

Complex system approaches in watershed governance: Identification of research trends, methods, and future direction

Sustainable Futures
Watershed governance is a complex challenge that integrates environmental, social, and institutional dimensions. Traditional approaches often fail to capture the intricate interdependencies of hydrological, ecological, and governance systems.
Sapen Sartika Unyi Putri, Ida Widianingsih, Anggia Utami Dewi, Indra Gunawan   +3 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Adapting to climate change and multi-risk governance: toward sustainable adaptation and enhancing urban resilience—Indonesia

Discover Applied Sciences
Climate change has contributed to an increase in natural catastrophes over the past five years in Indonesia, causing various forms of damage in urban areas and posing a severe danger to multi-risk governance for municipal governments in Indonesia.
Abdillah Abdillah, Ida Widianingsih, Rd Ahmad Buchari, Heru Nurasa   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source