Results 121 to 130 of about 773,976 (338)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Direct laser acceleration in varying plasma density profiles
New Journal of PhysicsDirect laser acceleration has proven to be an efficient source of high-charge electron bunches and high brilliance x-rays. However, an analytical description of the acceleration in the interaction with varying plasma density targets is still missing ...
R Babjak, B Martinez, M Krus, M Vranic
doaj +1 more source
Adaptive Multi-Dimensional Particle In Cell
, 2008 Kinetic Particle In Cell (PIC) methods can extend greatly their range of applicability if implicit time differencing and spatial adaption are used to address the wide range of time and length scales typical of plasmas. For implicit differencing, we refer the reader to our recent summary of the implicit moment PIC method implemented in our CELESTE3D ...
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Particle-in-Cell Simulations of PerpendicularSupernova Shock Fronts [PDF]
, 2015 The origin of cosmic rays was the subject of several studies for over a century. The investigations done within this dissertation are one small step to shed some more light on this mystery. Locating the sources of cosmic rays is not trivial due to the interstellar magnetic field.
openaire +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Nuclear FusionThe heat flux control of the divertor plate via strike-point splitting generated by biased targets was proposed in the HL-2A tokamak (Cui et al 2021 Fusion Eng. Des. 173 112963).
B.T. Cui +12 more
doaj +1 more source
Design and Simulation of a 3-MW L-Band Magnetron for Vehicle Stop System
IEEE AccessThis paper presents a design and simulation of a 3-MW-class L-band magnetron. The magnetron has 12 hole-and-slot resonators with double-strapped wires to eliminate the mode change during operation.
Hai Quan Ho +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source