Results 21 to 30 of about 24,141 (294)

The RUNX Family Defines Trk Phenotype and Aggressiveness of Human Neuroblastoma through Regulation of p53 and MYCN

Cells, 2023
The Runt-related transcription factor (RUNX) family, which is essential for the differentiation of cells of neural crest origin, also plays a potential role in neuroblastoma tumorigenesis. Consecutive studies in various tumor types have demonstrated that
Kiyohiro Ando, Akira Nakagawara
doaj   +1 more source

Acceleration or Brakes: Which Is Rational for Cell Cycle-Targeting Neuroblastoma Therapy?

Biomolecules, 2021
Unrestrained proliferation is a common feature of malignant neoplasms. Targeting the cell cycle is a therapeutic strategy to prevent unlimited cell division.
Kiyohiro Ando, Akira Nakagawara
doaj   +1 more source

The Majority of United States Citizens With Cancer do not Have Access to Carbon Ion Radiotherapy

Frontiers in Oncology, 2022
As of December 31, 2020, there were 12 facilities located in Asia and Europe which were treating cancer patients with carbon ion radiotherapy (CIRT). Between June 1994 and December 2020, 37,548 patients were treated with CIRT worldwide.
Robert L. Foote, Hirohiko Tsujii, Reiko Imai, Hiroshi Tsuji, Eugen B. Hug, Tatsuaki Kanai, Jiade J. Lu, Juergen Debus, Rita Engenhart-Cabillic, Anita Mahajan   +9 more
doaj   +1 more source

Multi-Institutional Retrospective Analysis of the Outcomes of Proton Beam Therapy for Patients With 1 to 3 Pulmonary Oligometastases From Various Primary Cancers

Advances in Radiation Oncology, 2021
Purpose: Our purpose was to evaluate the efficacy of proton beam therapy (PBT) in patients with 1 to 3 pulmonary oligometastases from various primary cancers in Japan.
Norihiro Aibe, MD, PhD, Hiroyuki Ogino, MD, PhD, Satoshi Teramukai, PhD, Hideya Yamazaki, MD, PhD, Hiromitsu Iwata, MD, PhD, Yoshiro Matsuo, MD, PhD, Tomoaki Okimoto, MD, PhD, Masao Murakami, MD, PhD, Motohisa Suzuki, MD, Takeshi Arimura, MD, PhD, Takashi Ogino, MD, PhD, Shigeyuki Murayama, MD, PhD, Hideyuki Harada, MD, PhD, Masaki Nakamura, MD, PhD, Tetsuo Akimoto, MD, PhD, Hideyuki Sakurai, MD, PhD   +15 more
doaj   +1 more source

Considerations for Upright Particle Therapy Patient Positioning and Associated Image Guidance

Frontiers in Oncology, 2022
Particle therapy is a rapidly growing field in cancer therapy. Worldwide, over 100 centers are in operation, and more are currently in construction phase.
Lennart Volz, Lennart Volz, Yinxiangzi Sheng, Yinxiangzi Sheng, Marco Durante, Marco Durante, Christian Graeff, Christian Graeff   +7 more
doaj   +1 more source

Study of an Online Plan Verification Method and the Sensitivity of Plan Delivery Accuracy to Different Beam Parameter Errors in Proton and Carbon Ion Radiotherapy

Frontiers in Oncology, 2021
For scanning beam particle therapy, the plan delivery accuracy is affected by spot size deviation, position deviation and particle number deviation.
Jun Zhao, Jun Zhao, Jun Zhao, Jun Zhao, Zhi Chen, Xianwei Wu, Ying Xing, Yongqiang Li   +7 more
doaj   +1 more source

Robust Angle Selection in Particle Therapy

Frontiers in Oncology, 2021
The popularity of particle radiotherapy has grown exponentially over recent years owing to the marked advantage of the depth–dose curve and its unique biological property. However, particle therapy is sensitive to changes in anatomical structure, and the
Yuan Zhou, Yang Li, Yang Li, Yoshiki Kubota, Makoto Sakai, Tatsuya Ohno, Tatsuya Ohno   +6 more
doaj   +1 more source

Charged Particle Therapy with Mini-Segmented Beams [PDF]

Frontiers in Oncology, 2015
One of the fundamental attributes of proton therapy and carbon ion therapy is the ability of these charged particles to spare tissue distal to the targeted tumor. This significantly reduces normal tissue toxicity and has the potential to translate to a wider therapeutic index.
Dilmanian, F. Avraham, Eley, John G., Rusek, Adam, Krishnan, Sunil   +3 more
openaire   +3 more sources

Particle radiation therapy in the management of adult high-grade glioma: A narrative review

Glioma, 2020
This narrative review summarizes the current status of the use of particle radiation therapy on the treatment of adult malignant gliomas. Due to the unique physical property, particle (e.g., proton or carbon-ion) beam radiation therapy can improve ...
Lin Kong, Jiade J Lu
doaj   +1 more source

From Photon Beam to Accelerated Particle Beam: Antimetastasis Effect of Combining Radiotherapy With Immunotherapy

Frontiers in Public Health, 2022
Cancer is one of the major diseases that seriously threaten the human health. Radiotherapy is a common treatment for cancer. It is noninvasive and retains the functions of the organ where the tumor is located.
Liqiu Ma, Liqiu Ma
doaj   +1 more source