Results 61 to 70 of about 1,509,399 (232)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Parallelized Particle and Gaussian Sum Particle Filters for Large Scale Freeway Traffic Systems [PDF]
, 2012 Large scale traffic systems require techniques able to: 1) deal with high amounts of data and heterogenous data coming from different types of sensors, 2) provide robustness in the presence of sparse sensor data, 3) incorporate different models that can ...
Gning, Amadou +7 more
core +1 more source
Model Adaptation for Prognostics in a Particle Filtering Framework [PDF]
International Journal of Prognostics and Health Management, 2011 One of the key motivating factors for using particle filters for prognostics is the ability to include model parameters as part of the state vector to be estimated.
Bhaskar Saha, Kai Goebel
doaj
Improved Parallel Resampling Methods for Particle Filtering
IEEE Access, 2019 Particle filter techniques are common methods used to estimate the evolving state of nonlinear, non-Gaussian time-variant systems by utilizing a periodic sequence of noisy measurements.
Matthew A. Nicely, B. Earl Wells
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Particle Filters for Markov Switching Stochastic Volatility Models [PDF]
This paper proposes an auxiliary particle filter algorithm for inference in regime switching stochastic volatility models in which the regime state is governed by a first-order Markov chain.
Boda Kang, Yun Bao, Carl Chiarella
core
Identifying Uncertainty Distributions and Confidence Regions of Power Plant Parameters
IEEE Access, 2017 Power system operators, when obtaining a model's parameter estimates; require additional information to guide their decision on a model's acceptance.
Tetiana Bogodorova +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Particle filters for combined state and parameter estimation. [PDF]
, 2001 Filtering is a method of estimating the conditional probability distribution of a signal based upon a noisy, partial, corrupted sequence of observations of the signal.
Chan, Hubert, Kouritzin, Michael
core +1 more source