Results 31 to 40 of about 22,766 (290)

The evolution of dark matter substructure [PDF]

open access: yes, 2001
This thesis investigates the dynamical evolution of systems orbiting within deeper potentials. Initially we use a simple satellite-halo interaction to study the dynamical processes that act on orbiting systems and we compare these results to analytical ...
Roldán, Carlos Antonio Calcáneo
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Enhancement of p-wave dark matter annihilation by quasi-bound states

open access: yesJournal of High Energy Physics
We scrutinize the Sommerfeld enhancement in dark matter pair annihilation for p-wave and higher-ℓ partial waves. For the Yukawa potential these feature a super-resonant Breit-Wigner peak in their velocity-dependence close to Sommerfeld resonances as well
Martin Beneke   +3 more
doaj   +1 more source

Multilepton signatures from dark matter at the LHC

open access: yesJournal of High Energy Physics, 2022
Leptonic signatures of Dark Matter (DM) are one of the cleanest ways to discover such a secluded form of matter at high energy colliders. We explore the full parameter space relevant to multi-lepton (2- and 3-lepton) signatures at the Large Hadron ...
Alexander Belyaev   +4 more
doaj   +1 more source

Limits on spin-dependent WIMP-proton cross-sections using the DRIFT-IId directional dark matter detector [PDF]

open access: yes, 2011
The nature of dark matter remains one of the biggest questions in physics today. Weakly Interacting Massive Particles (WIMPs) are a particularly well motivated candidate for the missing matter that makes up 85% of the mass of the Universe.
Pipe, Mark
core  

Particle Dark Matter

open access: yes, 2010
Dark matter is among the most important open problems in modern physics. Aimed at graduate students and researchers, this book describes the theoretical and experimental aspects of the dark matter problem in particle physics, astrophysics and cosmology ...

core   +1 more source

Investigating the Nature of Dark Matter with Strong Gravitational Lensing [PDF]

open access: yes, 2020
Dark matter makes up most of the mass in the Universe, and yet its particle nature remains unknown. Structure formation arguments provide a promising avenue to address this confounding mystery, as the mass and formation mechanism of the dark matter ...
Gilman, Daniel Alejandro
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Search for dark matter at colliders

open access: yes, 2017
Among the numerous proposals to explain the nature of dark matter, there is the weakly interacting massive particle (WIMP) scenario, which is based on a simple assumption that dark matter was in thermal equilibrium in the early hot Universe, and its ...
Buchmueller, Oliver,   +3 more
core   +2 more sources

Higgs portal dark matter freeze-in at stronger coupling: observational benchmarks

open access: yesJournal of High Energy Physics
We study freeze-in production of Higgs portal dark matter (DM) at temperatures far below the dark matter mass. The temperature of the Standard Model (SM) thermal bath may have never been high such that dark matter production via thermal emission has been
Giorgio Arcadi   +3 more
doaj   +1 more source

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