Results 41 to 50 of about 284,741 (271)
Freezing-in hadrophilic dark matter at low reheating temperatures
Journal of High Energy Physics, 2023 If the reheating temperature at the end of inflation is low, of order 10 MeV, then dark matter produced through ultraviolet freeze-in has a large direct detection cross section. We study such a scenario in which dark matter is hadrophilic.
Prudhvi N. Bhattiprolu +3 more
doaj +1 more source
IceCube: The Cubic Kilometer Neutrino Telescope at the South Pole
, 2004 Search for ultra high-energy neutrino induced reactions, as part of a comprehensive probe of the neutrino sky and also investigation of the particle nature of the dark matter, with unique sensitivity to cold dark matter particles are described.
Fazely, A. R.
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Higgs portal dark matter freeze-in at stronger coupling: observational benchmarks
Journal of High Energy PhysicsWe study freeze-in production of Higgs portal dark matter (DM) at temperatures far below the dark matter mass. The temperature of the Standard Model (SM) thermal bath may have never been high such that dark matter production via thermal emission has been
Giorgio Arcadi +3 more
doaj +1 more source
Physics Letters BWe investigate the production of non-thermal fermionic dark matter particles during the reheating era following slow roll inflation, driven by inflaton $φ$ non-minimally coupled to the curvature scalar, $\mathcal{R}$. Two types of non-minimal couplings are considered: $ξφ^2\cal{R}$ for both natural (referred to as NM-N) and for Coleman-Weinberg ...
Anish Ghoshal +3 more
openaire +3 more sources
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
The quintuplet annihilation spectrum
Journal of High Energy PhysicsWe extend the Effective Field Theory of Heavy Dark Matter to arbitrary odd representations of SU(2) and incorporate the effects of bound states. This formalism is then deployed to compute the gamma-ray spectrum for a 5 of SU(2): quintuplet dark matter ...
Matthew Baumgart +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Dark matter from a conformal Dark Sector
Journal of High Energy Physics, 2023 We consider theories in which a dark sector is described by a Conformal Field Theory (CFT) over a broad range of energy scales. A coupling of the dark sector to the Standard Model breaks conformal invariance.
Sungwoo Hong +2 more
doaj +1 more source
Constraining scalar fields with stellar kinematics and collisional dark matter
, 2010 The existence and detection of scalar fields could provide solutions to long-standing puzzles about the nature of dark matter, the dark compact objects at the centre of most galaxies, and other phenomena.
A. Bernal +27 more
core +1 more source