Results 121 to 130 of about 164,484 (166)
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Particle Beams for Cancer Therapy
Clinical Oncology, 2003Particle beams from protons to carbon ions have a number of important advantages for radiation therapy. Besides the physical selectivity that makes ions especially efficient for deep-seated tumours and tumours close to critical organs, carbon ions with their enhanced relative biological effectiveness offer an additional biological advantage for slow ...
W K, Weyrather, J, Debus
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Radiation Therapy With Charged Particles
Seminars in Radiation Oncology, 2006Charged particle beams can offer an improved dose conformation to the target volume as compared with photon radiotherapy, with better sparing of normal tissue structures close to the target. In addition, beams of ions heavier than (4)He exhibit a strong increase of the linear energy transfer in the Bragg peak as compared with the entrance region. These
Daniela, Schulz-Ertner +2 more
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Particle-Mediated Gene Therapy of Wounds
Wound Repair and Regeneration, 2000Gene therapy is becoming a reality, and it is a particularly attractive approach for wound healing, because the wound site is often exposed, the treatment and condition should be transient, and gene products such as growth factors and cytokines suffer from problems with bioavailability and stability.
J M, Davidson, T, Krieg, S A, Eming
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Antiviral therapy with small particle aerosols
European Journal of Clinical Microbiology & Infectious Diseases, 1988The generation and use of small particle aqueous aerosols (1.23 microns aerodynamic mass median diameter, GSD = 2.0 microns) containing ribavirin is described. Administered via aerosol, ribavirin will be deposited rather uniformly on the surface of the nasopharynx, the tracheobronchial tree and in the pulmonary area.
V, Knight, B, Gilbert
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Alpha-particles for targeted therapy
Advanced Drug Delivery Reviews, 2008Alpha-particles are helium nuclei that deposit DNA damaging energy along their track that is 100 to 1000 times greater than that of conventionally used beta-particle emitting radionuclides for targeted therapy; the damage caused by alpha-particles is predominately double-stranded DNA breaks severe enough so as to be almost completely irreparable.
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The British Journal of Radiology, 2006
Among the most important decisions facing the British Government regarding the treatment of cancer in the National Health Service (NHS) is the purchase of charged particle therapy (CPT) centres. CPT is different from conventional radiotherapy: the dose is deposited far more selectively in Bragg Peaks by either protons or "heavy" ions, such as carbon ...
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Among the most important decisions facing the British Government regarding the treatment of cancer in the National Health Service (NHS) is the purchase of charged particle therapy (CPT) centres. CPT is different from conventional radiotherapy: the dose is deposited far more selectively in Bragg Peaks by either protons or "heavy" ions, such as carbon ...
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American Journal of Clinical Oncology, 2008
With the arrival of 3-dimensional conformal radiation therapy and intensity modulated radiation therapy, radiation dose distributions in radiation oncology have improved dramatically over the past couple of decades. As part of a natural progression there recently has been a resurgence of interest in hadron therapy, specifically charged particle therapy,
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With the arrival of 3-dimensional conformal radiation therapy and intensity modulated radiation therapy, radiation dose distributions in radiation oncology have improved dramatically over the past couple of decades. As part of a natural progression there recently has been a resurgence of interest in hadron therapy, specifically charged particle therapy,
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Percutaneous Transcatheter Particle Therapies
2019Given that only 20–30% of patients with hepatocellular carcinoma and colorectal liver metastases present with resectable disease, there has been an increasing role for the use of percutaneous transcatheter particle therapies in the management of unresectable hepatic malignancies.
Grace C. Lee +2 more
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Cancer, 1976
Particle radiation therapy has the potential for immediate and sustained favorable impact on management of the cancer patient by providing better local tumor control. Scientific knowledge and expertise are immediately available to mount effective clinical studies of fast neurons, protons, and helium ions, and to initiate necessary preliminary studies ...
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Particle radiation therapy has the potential for immediate and sustained favorable impact on management of the cancer patient by providing better local tumor control. Scientific knowledge and expertise are immediately available to mount effective clinical studies of fast neurons, protons, and helium ions, and to initiate necessary preliminary studies ...
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2005
The role of monoclonal antibodies (MAbs) in the treatment of malignancies has increased dramatically over the past decade. Three unlabeled MAbs—rituximab (Rituxan; IDEC Pharmaceuticals, San Diego, CA, and Genentech, Inc., South San Francisco, CA), trastuzumab (Herceptin; Genentech, Inc., South San Francisco, CA), and alemtuzumab (Campath-1H; Burroughs ...
John M. Burke +2 more
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The role of monoclonal antibodies (MAbs) in the treatment of malignancies has increased dramatically over the past decade. Three unlabeled MAbs—rituximab (Rituxan; IDEC Pharmaceuticals, San Diego, CA, and Genentech, Inc., South San Francisco, CA), trastuzumab (Herceptin; Genentech, Inc., South San Francisco, CA), and alemtuzumab (Campath-1H; Burroughs ...
John M. Burke +2 more
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