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Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, EarlyView.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu +10 more
wiley +1 more source
Shellac‐Mediated Assembly of Nanoparticles for mRNA Delivery
Advanced Healthcare Materials, EarlyView.A shellac‐mediated nanoparticle assembly strategy is presented, involving the complexation of mRNA and low‐molecular‐weight cationic molecules (e.g., polyethyleneimine, chitosan, lipids, and poly‐l‐lysine), followed by capping with shellac. This nanoparticle platform enables mRNA transfection following intravenous injection and facilitates gene editing
Meizhang Lu +7 more
wiley +1 more source
The Value of PET/CT in Particle Therapy Planning of Various Tumors with SSTR2 Receptor Expression: Comparative Interobserver Study. [PDF]
Cancers (Basel)Lütgendorf-Caucig C +11 more
europepmc +1 more source
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2022
Particle therapy is a form of radiation therapy in which high energy ionised particles, most commonly protons or neutrons, are aimed at the target tissue. In the context of breast cancer treatment, proton beam therapy is the most commonly used particle therapy and is therefore the focus of this section.
Kirby, Anna M., Boersma, Liesbeth J.
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Particle therapy is a form of radiation therapy in which high energy ionised particles, most commonly protons or neutrons, are aimed at the target tissue. In the context of breast cancer treatment, proton beam therapy is the most commonly used particle therapy and is therefore the focus of this section.
Kirby, Anna M., Boersma, Liesbeth J.
openaire +1 more source
Cancer, 1985
Current interest in attempting to identify any therapeutic advantages of beams of heavy particles (heavier than electrons) over photons is based on differences in physical absorption and radiobiologic interactions. The article discusses: dose distributions in tissue, which are markedly different for particles than for high energy photons and so may be ...
openaire +2 more sources
Current interest in attempting to identify any therapeutic advantages of beams of heavy particles (heavier than electrons) over photons is based on differences in physical absorption and radiobiologic interactions. The article discusses: dose distributions in tissue, which are markedly different for particles than for high energy photons and so may be ...
openaire +2 more sources
Motion in radiotherapy: particle therapy
Physics in Medicine and Biology, 2011Charged particle beam radiotherapy requires dedicated measures to compensate for the dosimetric influence of inter- and intra-fractional target motion. Independent of the delivery technique, these measures have to incorporate the strong influence of the radiological depth on the delivered dose.
C. Bert, DURANTE, MARCO
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