Results 71 to 80 of about 1,058,569 (267)

Effect of alkali metal salt addition on disintegration of titania particles precipitated from tetraethyl orthotitanate in ethanol

open access: yesInternational Journal of Ceramic Engineering & Science
Inline (or in situ) photon density wave spectroscopy was used to monitor the disintegration of secondary titania particles into their primary particles.
Sebastian Zimmermann   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

On-Site Sensitive Colorimetry for Free Cyanide by Using Ion-Pair Solid-Phase Extraction with Sedimentable Dispersed Particulates and Mobile Photography Box

open access: yesMolecules
We propose a sensitive and simple colorimetric method using dispersed particle extraction for the highly sensitive detection of free cyanide in water samples.
Nozomi Kohama   +5 more
doaj   +1 more source

THE EFFECT OF CAVITATION TREATMENT ON THE EXTINGUISHING OF PARTICLES OF OILS IN FUEL BOILERS

open access: yesИзвестия высших учебных заведений: Проблемы энергетики, 2019
The difficulties of burning the watered fuel oil used at the TPP as a reserve fuel for boilers are associated with its preparation by heating to reduce viscosity and the choice of a method of spraying with nozzles into the combustion zone. The quality of
M. A. Taymarov   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Particle astrophysics from the particle perspective [PDF]

open access: yesAIP Conference Proceedings, 1994
Talk presented at the Lepton-Photon Symposium, 1993, some discussion of axions and anthropic principle revised, 34pp, SCIPP 93 ...
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Microneedle Coating Techniques for Transdermal Drug Delivery

open access: yesPharmaceutics, 2015
Drug administration via the transdermal route is an evolving field that provides an alternative to oral and parenteral routes of therapy. Several microneedle (MN) based approaches have been developed.
Rita Haj-Ahmad   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy