Results 81 to 90 of about 3,733,318 (295)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
German bloss-questions as extreme ignorance questions
Linguistica Brunensia, 2020 We analyze German bloss as a marker of extreme ignorance questions Q, basically indicating that the speaker has dismissed answers to Q that she initially considered likely. We argue that bloss in questions is used in three varieties that all play on this
Regine Eckardt, Qi Yu
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
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Литьë и металлургияThis article presents the findings of research on the impact of thermal diffusion galvanizing duration and the particle size of zinc dust waste in the galvanizing mixture on the properties and structure of the zinc coating.
N. I. Urbanovich +3 more
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The Properties of Kaolin from Different Locations and Their Impact on Casting Rate
KONA Powder and Particle Journal, 2019 It has been well known that mineral samples from different locations and origins can exhibit a significant shift in their properties and behavior. The present study of three samples of kaolin from a wide set of origin of deposits, composition, and ...
Mervat Said Hassan Badr +7 more
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Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
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Surface analysis of cannabigerol cocrystals: linking crystal structure to enhanced properties
IUCrJCannabigerol is a bioactive compound derived from Cannabis sativa. It displays many promising pharmaceutical and nutraceutical properties. Its use and research are complicated by its thermally unstable solid form with low solubility and needle habit ...
Eliška Zmeškalová +3 more
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
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Local univalence versus stability and causality in hydrodynamic models
European Physical Journal C: Particles and FieldsOur primary goal is to compare the analytic properties of hydrodynamic series with the stability and causality conditions applied to hydrodynamic modes. Analyticity, in this context, serves as a necessary condition for hydrodynamic series to behave as a ...
Roya Heydari, Farid Taghinavaz
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